Abstract
Karate is a locally used pesticide has lambda cyhalothrin (-Cyhalothrin) as an active ingredient. To determine the acute toxicity fry of Cyprinus carpio were exposed to 0.00 0.08 0.16 0.2 0.24 0.32 and 0.4 L L-1 of Karate for 96 h in a static bioassay. The 96 h LC50value was determined by using Arithmetic method and found to be 0.160 L L-1. Fry of C. carpio were exposed to 10% (0.16 L L-1) and 20% (0.032 L L-1) lethal concentration of pesticide and observed the effects on total protein content and acetylcholinestrase (AChE) activity in brain liver and muscle tissues. The total protein content and AChE activity in different tissues of fish decreased in concentration dependent manner and showed tissue specific pattern. The maximum reduction of AChE activity was observed in brain followed by muscle and liver tissues while liver showed higher decline in protein content as compared to muscle and brain tissues. The minimum reduction of protein content in response to Karate was observed in brain tissues. The study clearly indicated the toxicity of Karate to fish and suggest the prevention of indiscriminate use of this pesticide. Copyright 2014 Friends Science Publishers.