Abstract
Background: Sudan is a big country with a high frequency of Leishmania of both types, visceral and cutaneous, with several clinical manifestations. However, little is known about the hematological profiles in patients with cutaneous Leishmania (CL) in this population and other ethnic groups.
Aim: To estimate the complete blood count (CBC) in the Cutaneous Leishmania of Sudanese patients.
Methods: In a case-control study three hundred participants were recruited, comprising 200 carriers and 100 healthy individuals. In each case, five ml of venous blood was taken into an EDTA container and the CBC estimated using a hematology analyzer. The SPSS version 21 of Sysmex was used for data analysis.
Results: The majority (57%) of Leishmania patients were male and a significant CBC increase was observed in the lymphocyte. Mixed WBCs and platelet counts for Leishmania patients were (34.2 +/- 11.7; 11.6 +/- 4.6 and 243.3 +/- 76.6), compared to the control (28.54 +/- 9.02; 9.6 +/- 4.2 and 198.9 +/- 72.2), with p values (0.000; 0.000 and 0.000), respectively.
Conclusion: The higher count of lymphocytes, mixed WBCs and platelets, suggests an elicited cellular immunity reaction in Leishmania patients. We believe that more studies into haemogram parameters are necessary.