Abstract
Infertility is considered an emerging issue among the Saudi population in which it accounts for around 2.2% of cases in Saudi Arabia. Numerous studies examined the association between reproductive hormone changes and infertility; however, there is still a gap in the literature regarding the hormonal changes among Saudi female. Therefore, this study aimed to evaluate the reproductive hormonal changes in females with infertility. A rcross-sectional study have been carried out at King Abdulaziz Medical City (KAMC) hospital in Riyadh from 2017 through 2018. All Saudi females with primary and secondary infertility aged between 20 and 35 years were included in this study. The blood level of follicle-stimulating hormone (FSH), luteinizing hormone (LH), estrogen, prolactin, and progesterone were obtained from the medical record of those patients. A total of 81 infertile women were recruited for this study. 57(70%) of them were with primary infertility, where 24(30%) females were with secondary infertility. Patients with secondary infertility were older than patients with primary infertility (P<0.001). Similarly, the percentage of obese patients was higher compared to other Body Mass Index categories, and that was different between patients with primary and secondary infertility (p=0.02). Conclusion: This finding provides insight into infertility classification among Saudi infertile women and could be used as the first step in exploring infertility causes in all regions of Saudi Arabia in addition to other factors.