Abstract
In the present work an easy-to-make and sensitive sensor based on ZnO nanoparticle (ZnO/NP) ionic liquid (IL) composite for voltammetric sensing of isoprenaline (ISN) in real samples was developed. The synthesized nanoparticle was characterized with different methods such as transmission electron microscopy (TEM) and X-ray diffraction (XRD). The modified ZnO/NP ionic liquid carbon paste electrode (ZnO/NP/IL/CPE) was used as an electrochemical sensor for the determination of trace amounts of ISN. The anodic peaks of ISN and aspirin (ASP) in their mixture can be well separated. At pH5.0 the two peaks are separated ca. 0.56 and 0.98V, respectively; hence ISN can be determined in the presence of ASP and more than 2.6 times of the current excess of ISN. The square wave (SW) voltammogram peak current of ISN and ASP increased linearly with their concentration in the ranges of 0.3–320μmolL−1 ISN and 0.7–950μmolL−1 ASP. The detection limits for ISN and ASP were 0.09 and 0.3μmolL−1, respectively. The suggestion sensor has been successfully applied for the assay of the above compounds in real samples such as drug and urine.
In this study we describe the application of ZnO nanoparticles and ionic liquid carbon paste electrode as high sensitive sensors for voltammetric determination of isoprenaline in the presence of aspirin for the first time. [Display omitted]
•Electrochemical behavior of isuprel study using modified carbon paste electrode•Synthesis and application of NiO/NPs as novel sensor for isuprel determination•This sensor is also used for the determination of isuprel in real samples.