Abstract
Aim: Patients with type 2 diabetes mellitus have an increased prevalence of dyslipidemia and are easy targets for cardiovascular diseases. This retrospective study investigated the serum lipid profile of patients with type 2 diabetes mellitus and assessed the relationship between HbA1c levels, lipid profile, and BMI to evaluate the importance of HbA1c as a predictor of dyslipidemia. Material and Methods: The study was conducted at the Diabetes Center of the Tertiary Care Hospital in Arar, Saudi Arabia. Demographic and biochemical data of 100 patients with type 2 diabetes were collected from electronic records of the hospital. Correlation analysis was performed to analyze the association between HbA1c, lipid profile and BMI. Results: The results revealed an increase in the levels of fasting blood glucose, blood urea nitrogen, total protein and HbA1C levels, accompanied by a decrease in albumin levels among both male and female patients with no significant difference among the genders. The study also demonstrated an alteration in the lipid profile of the patients with elevated levels of total cholesterol, TAGs and LDL-C with a concomitant reduction in HDL-C levels. Correlation analysis demonstrated a significant (p<0.05) positive correlation between HbA1C and different lipids (total cholesterol, Triglyceride and LDL-C) and BMI. A significant (p<0.05) negative correlation was found between HbA1C and HDL-C levels. Discussion: The results indicate that in addition to as a biomarker for glycemic control, HbA1c can also be used in predicting dyslipidemia associated with type 2 diabetes to prevent the development of cardiovascular diseases.