Abstract
Introduction: The aim of the study was to identify the status of therapeutic regimens administration in Sudan during Ramadan month among patients observing the fast of the holy month. Methods: A cross-sectional, study was conducted at public teaching hospitals on patients receiving drug prescriptions and committed to fasting. Patients were interviewed using predesigned questionnaires. They were personally interviewed with regards to their drugs use; regimens; and effectiveness of the drugs. Statistical evaluation was performed with statistical tool (SPSS) package for social science. Data were analyzed by means of the Chi-square Test to compare the differences for various results. The differences were significant at p <= 0.05. Results: Two hundred patients participated in the study successfully. An excess of 85 % of the patients continued their daytime-fasting following physician counselling. Enteral administration prevailed, and so did BID regimens. Almost all took nocturnal doses. The drugs` effectiveness in 71% of the adults was not affected by fasting. Seventy three percent of the adults were facing difficulties with their drugs. The majority of cases were patients with upper respiratory tract infections (25.5%). Thirty one percent of the patiants used antibiotics. Conclusion: Findings are consistent with estimations elsewhere. Regimens were tailored to fit the break-fasting hours. A vista is open for clinical trials on the impact of daytime-fasting on the pharmacodynamic and pharmacokinetic behavior of essential drugs.