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Evidence for the presence of complement in human myelin
Journal article   Peer reviewed

Evidence for the presence of complement in human myelin

Y.H. Abdulla and Elizabeth McFarlane
Biochemical and biophysical research communications, Vol.46(3), pp.1072-1073
16/02/1972
DOI: https://doi.org/10.1016/S0006-291X(72)80082-2
PMID: 5062422

Abstract

Human myelin suspension is agglutinated by rabbit anti-C′3 and anti-C′4 antibodies. Endotoxin Lipopolysaccaride, Zymosan, Cobra Factor, Inulin and Carragheenan, all complement activators, cause release of soluble proteins from myelin fragments. The release is prevented by prior treatment of the myelin preparation with anti-C′3 and anti-C′4 antibodies.

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