Abstract
Background: Cirrhosis is a condition in which the liver does not function properly due to long-term damage. It is the end stage of chronic liver disease clinically characterized by progressive liver failure, development of portal hypertension or hepatocellular carcinoma. Fibrosis occurs due to interaction between different cell types and ctokines. Profibrotic agents include type-2 CD4 positive lymphocytes, CD40 receptor, interaction and cytokines like IL-4, TGF beta, platelet derived growth factor.
Aim: To evaluate the relationship of liver cirrhosis and pulmonary fibrosis according to child's classification.
Duration and Place of Study: Six months from 01-07 2016 to 30-01-2017 at University College of Medicine and Dentistry, University of Lahore.
Methods: This is a case series description study. Seventy patients were included according to inclusion and exclusion criteria.
Conclusion: A significant relationship between cirrhosis of liver and pulmonary fibrosis and with advancement of child class, frequency of pulmonary fibrosis increases.