Abstract
One-pot synthesis of novel beta-lactam-grafted spiropyrrolidines has been accomplished in good yield via a facile [3+2] cycloaddition reaction of azomethine ylides, derived from beta-lactam aldehyde and sarcosine, with various p-substituted (E)-2-oxoindoline-3-ylidene acetophenone derivatives as dipolarophiles. The reaction gave excellent yields of the products when carried out under microwave irradiation.