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Facile and Convenient Synthesis of 1-Perfluoroalkyl-1,2,4-triazoles
Journal article   Peer reviewed

Facile and Convenient Synthesis of 1-Perfluoroalkyl-1,2,4-triazoles

M. Kammoun, A. Chihi, B. Hajjem, M. Bellassoued and Madiha Kamoun
Synthetic communications, Vol.38(1), pp.148-153
01/01/2008
DOI: https://doi.org/10.1080/00397910701651367

Abstract

imidates perfluoroalkylhydrazines perfluoroalkyltriazoles
Treatment of N-methylcarbonyl 1, N-phenylthioamido 2, and N-cyano 3 iminoethers with perfluoroalkylated hydrazines leads to 1-perfluoroalkyl-5-methyl-1,2,4- triazoles, 4,1-perfluoroalkyl-5-phenylamino-1,2,4-triazoles 5, and 1-perfluoroalkyl-5-amino-1,2,4-triazoles 6 in good yields. These compounds are screened for their biological activities.

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