Abstract
1,2-Dihydro-2-imino-6-(2-imino-2H-chromen-3-yl)-1,4-diphenyl-pyridine-3-carbonitrile 4 has been synthesized and reacted with ethyl cyanoacetate to yield the new 5-amino-1,7-dihydro-2-(2-imino-2H-chromen-3-yl)-7-oxo-1,4-diphenyl-1,8-naphthyridine-6-carbonitrile 6, which consider a good and available starting intermediate for synthesis of series of functionalized chromenes. So, the compound 6 was utilized as a key for the synthesis of some new pyrimido[5,4-c][1,8]naphthyridinones, pyrido[2,3-c][1,6]naphthyridinones, triazolo[3',4':1,6]triazino][5,4-c][1,8]naphthyridinones, triazolo[2',3':1,6]pyrimido[4,5-c][1,8]naphthyridinones, triazepino[6,5-c][1,8]naphthyridinone, and triazino[5,4-c][1,8]naphthyridinones. The structures of these compounds were established by elemental analysis, IR, MS, and NMR spectral analysis. J. Heterocyclic Chem., (2012).