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Facile selective synthesis of new furo[3,4-d]-1,3-thiazoles
Journal article   Peer reviewed

Facile selective synthesis of new furo[3,4-d]-1,3-thiazoles

Ashraf A. Aly, Alaa A. Hassan, Husam R.M. Al-Qalawi and Esam A. Ishak
Journal of sulfur chemistry, Vol.33(4), pp.419-426
01/08/2012
DOI: https://doi.org/10.1080/17415993.2012.700458

Abstract

1,4-Diphenyl-but-2-yne-1,4-dione bi-nucleophilic attack furo[3,4-d]-1,3-thiazoles N-aryl-hydrazinecarbothioamides triethylamine
In presence of triethylamine, the reaction of substituted 2-aroyl-hydrazinecarbothioamides with 1,4-Diphenyl-but-2-yne-1,4-dione afforded novel furo[3,4-d]-1,3-thiazoles in good yield. The reaction mechanism suggests that the second molecule of 1,4-Diphenyl-but-2-yne-1,4-dione behaved as an oxidizing agent.

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