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Facile synthesis of novel polysubstituted thiophene and benzo[g]thiazo[3,2-a]pyridine
Journal article   Peer reviewed

Facile synthesis of novel polysubstituted thiophene and benzo[g]thiazo[3,2-a]pyridine

M A Raslan, M A Khalil, S M Sayed and A M Farag
Heterocyclic communications, Vol.5(2), pp.167-171
01/01/1999

Abstract

Chemistry Chemistry, Organic Physical Sciences Science & Technology
2-cyanomethylbenzothiazole 1 reacts with acetone derivatives 2a-d, or acetonitrile derivative 6a-d in the presence of sulfur and triethylamine afforded the novel polysubstituted thiophene. Treatment of 1 with alkylidenemalononitrile derivatives IIa-h resulted in the formation of benzo[g]thiazo[3,2-a]pyridines in high yield.

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