Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes

Laura Fachal; Hugues Aschard; Jonathan Beesley; Daniel R. Barnes; Jamie Allen; Siddhartha Kar; Karen A. Pooley; Joe Dennis; Kyriaki Michailidou; Constance Turman; Penny Soucy; Audrey Lemacon; Michael Lush; Jonathan P. Tyrer; Maya Ghoussaini; Mahdi Moradi Marjaneh; Xia Jiang; Simona Agata; Kristiina Aittomaki; M. Rosario Alonso; Irene L. Andrulis; Hoda Anton-Culver; Natalia N. Antonenkova; Adalgeir Arason; Volker Arndt; Kristan J. Aronson; Banu K. Arun; Bernd Auber; Paul L. Auer; Jacopo Azzollini; Judith Balmana; Rosa B. Barkardottir; Daniel Barrowdale; Alicia Beeghly-Fadiel; Javier Benitez; Marina Bermisheva; Katarzyna Bialkowska; Amie M. Blanco; Carl Blomqvist; William Blot; Natalia Bogdanova; Stig E. Bojesen; Manjeet K. Bolla; Bernardo Bonanni; Ake Borg; Kristin Bosse; Hiltrud Brauch; Hermann Brenner; Ignacio Briceno; Ian W. Brock; Angela Brooks-Wilson; Thomas Bruening; Barbara Burwinkel; Saundra S. Buys; Qiuyin Cai; Trinidad Caldes; Maria A. Caligo; Nicola J. Camp; Ian Campbell; Federico Canzian; Jason S. Carroll; Brian D. Carter; Jose E. Castelao; Jocelyne Chiquette; Hans Christiansen; Wendy K. Chung; Kathleen B. M. Claes; Christine L. Clarke; J. Margriet Collee; Sten Cornelissen; Fergus J. Couch; Angela Cox; Simon S. Cross; Cezary Cybulski; Kamila Czene; Mary B. Daly; Miguel de la Hoya; Peter Devilee; Orland Diez; Yuan Chun Ding; Gillian S. Dite; Susan M. Domchek; Thilo Doerk; Isabel dos-Santos-Silva; Arnaud Droit; Stephane Dubois; Martine Dumont; Mercedes Duran; Lorraine Durcan; Miriam Dwek; Diana M. Eccles; Christoph Engel; Mikael Eriksson; D. Gareth Evans; Peter A. Fasching; Olivia Fletcher; Giuseppe Floris; Henrik Flyger; Lenka Foretova; William D. Foulkes; Eitan Friedman; Lin Fritschi; Debra Frost; Marike Gabrielson; Manuela Gago-Dominguez; Gaetana Gambino; Patricia A. Ganz; Susan M. Gapstur; Judy Garber; Jose A. Garcia-Saenz; Mia M. Gaudet; Vassilios Georgoulias; Graham G. Giles; Gord Glendon; Andrew K. Godwin; Mark S. Goldberg; David E. Goldgar; Anna Gonzalez-Neira; Maria Grazia Tibiletti; Mark H. Greene; Mervi Grip; Jacek Gronwald; Anne Grundy; Pascal Guenel; Eric Hahnen; Christopher A. Haiman; Niclas Hakansson; Per Hall; Ute Hamann; Patricia A. Harrington; Jaana M. Hartikainen; Mikael Hartman; Wei He; Catherine S. Healey; Bernadette A. M. Heemskerk-Gerritsen; Jane Heyworth; Peter Hillemanns; Frans B. L. Hogervorst; Antoinette Hollestelle; Maartje J. Hooning; John L. Hopper; Anthony Howell; Guanmengqian Huang; Peter J. Hulick; Evgeny N. Imyanitov; Claudine Isaacs; Motoki Iwasaki; Agnes Jager; Milena Jakimovska; Anna Jakubowska; Paul A. James; Ramunas Janavicius; Rachel C. Jankowitz; Esther M. John; Nichola Johnson; Michael E. Jones; Arja Jukkola-Vuorinen; Audrey Jung; Rudolf Kaaks; Daehee Kang; Pooja Middha Kapoor; Beth Y. Karlan; Renske Keeman; Michael J. Kerin; Elza Khusnutdinova; Johanna Kiiski; Judy Kirk; Cari M. Kitahara; Yon-Dschun Ko; Irene Konstantopoulou; Veli-Matti Kosma; Stella Koutros; Katerina Kubelka-Sabit; Ava Kwong; Kyriacos Kyriacou; Yael Laitman; Diether Lambrechts; Eunjung Lee; Goska Leslie; Jenny Lester; Fabienne Lesueur; Annika Lindblom; Wing-Yee Lo; Jirong Long; Artitaya Lophatananon; Jennifer T. Loud; Jan Lubinski; Robert J. MacInnis; Tom Maishman; Enes Makalic; Arto Mannermaa; Mehdi Manoochehri; Siranoush Manoukian; Sara Margolin; Maria Elena Martinez; Keitaro Matsuo; Tabea Maurer; Dimitrios Mavroudis; Rebecca Mayes; Lesley McGuffog; Catriona McLean; Noura Mebirouk; Alfons Meindl; Austin Miller; Nicola Miller; Marco Montagna; Fernando Moreno; Kenneth Muir; Anna Marie Mulligan; Victor M. Munoz-Garzon; Taru A. Muranen; Steven A. Narod; Rami Nassir; Katherine L. Nathanson; Susan L. Neuhausen; Heli Nevanlinna; Patrick Neven; Finn C. Nielsen; Liene Nikitina-Zake; Aaron Norman; Kenneth Offit; Edith Olah; Olufunmilayo Olopade; Hakan Olsson; Nick Orr; Ana Osorio; V. Shane Pankratz; Janos Papp; Sue K. Park; Tjoung-Won Park-Simon; Michael T. Parsons; James Paul; Inge Sokilde Pedersen; Bernard Peissel; Beth Peshkin; Paolo Peterlongo; Julian Peto; Dijana Plaseska-Karanfilska; Karolina Prajzendanc; Ross Prentice; Nadege Presneau; Darya Prokofyeva; Miquel Angel Pujana; Katri Pylkas; Paolo Radice; Susan J. Ramus; Johanna Rantala; Rohini Rau-Murthy; Gad Rennert; Harvey A. Risch; Mark Robson; Atocha Romero; Maria Rossing; Emmanouil Saloustros; Estela Sanchez-Herrero; Dale P. Sandler; Marta Santamarina; Christobel Saunders; Elinor J. Sawyer; Maren T. Scheuner; Daniel F. Schmidt; Rita K. Schmutzler; Andreas Schneeweiss; Minouk J. Schoemaker; Ben Schoettker; Peter Schuermann; Christopher Scott; Rodney J. Scott; Leigha Senter; Caroline M. Seynaeve; Mitul Shah; Priyanka Sharma; Chen-Yang Shen; Xiao-Ou Shu; Christian F. Singer; Thomas P. Slavin; Snezhana Smichkoska; Melissa C. Southey; John J. Spinelli; Amanda B. Spurdle; Jennifer Stone; Dominique Stoppa-Lyonnet; Christian Sutter; Anthony J. Swerdlow; Rulla M. Tamimi; Yen Yen Tan; William J. Tapper; Jack A. Taylor; Manuel R. Teixeira; Maria Tengstroem; Soo Hwang Teo; Mary Beth Terry; Alex Teul; Mads Thomassen; Darcy L. Thull; Marc Tischkowitz; Amanda E. Toland; Rob A. E. M. Tollenaar; Ian Tomlinson; Diana Torres; Gabriela Torres-Mejia; Melissa A. Troester; Therese Truong; Nadine Tung; Maria Tzardi; Hans-Ulrich Ulmer; Celine M. Vachon; Christi J. van Asperen; Lizet E. van der Kolk; Elizabeth J. van Rensburg; Ana Vega; Alessandra Viel; Joseph Vijai; Maartje J. Vogel; Qin Wang; Barbara Wappenschmidt; Clarice R. Weinberg; Jeffrey N. Weitzel; Camilla Wendt; Hans Wildiers; Robert Winqvist; Alicja Wolk; Anna H. Wu; Drakoulis Yannoukakos; Yan Zhang; Wei Zheng; David Hunter; Paul D. P. Pharoah; Jenny Chang-Claude; Montserrat Garcia-Closas; Marjanka K. Schmidt; Roger L. Milne; Vessela N. Kristensen; Juliet D. French; Stacey L. Edwards; Antonis C. Antoniou; Georgia Chenevix-Trench; Jacques Simard; Douglas F. Easton; Peter Kraft; Alison M. Dunning; Veronique Mari; Pascaline Berthet; Laurent Castera; Dominique Vaur; Hakima Lallaoui; Yves-Jean Bignon; Nancy Uhrhammer; Valerie Bonadona; Christine Lasset; Francoise Revillion; Paul Vennin; Daniele Muller; Denise Molina Gomes; Olivier Ingster; Isabelle Coupier; Pascal Pujol; Marie-Agnes Collonge-Rame; Isabelle Mortemousque; Odile Bera; Mickaelle Rose; Amandine Baurand; Geoffrey Bertolone; Laurence Faivre; Hlne Dreyfus; Dominique Leroux; Laurence Venat-Bouvet; Stephane Bezieau; Capucine Delnatte; Jean Chiesa; Brigitte Gilbert-Dussardier; Paul Gesta; Fabienne Prieur Prieur; Myriam Bronner; Johanna Sokolowska; Florence Coulet; Nadia Boutry-Kryza; Alain Calender; Sophie Giraud; Melanie Leone; Sandra Fert-Ferrer; Yue Jiao; Fabienne Lesueur Lesueur; Emmanuelle Barouk-Simonet; Virginie Bubien; Michel Longy; Nicolas Sevenet; Laurence Gladieff; Christine Toulas; Audrey Reimineras; Hagay Sobol; Brigitte Bressac-de Paillerets; Odile Cabaret; Olivier Caron; Marine Guillaud-Bataille; Etienne Rouleau; Muriel Belotti; Bruno Buecher; Sandrine Caputo; Chrystelle Colas; Antoine De Pauw; Emmanuelle Fourme; Marion Gauthier-Villars; Lisa Golmard; Virginie Moncoutier; Claire Saule; Alan Donaldson; Alex Murray; Angela Brady; Carole Brewer; Caroline Pottinger; Clare Miller; David Gallagher; Helen Gregory; Jackie Cook; Jacqueline Eason; Julian Adlard; Julian Barwell; Kai-Ren Ong; Katie Snape; Lisa Walker; Louise Izatt; Lucy Side; Mark T. Rogers; Mary E. Porteous; Munaza Ahmed; Patrick J. Morrison; Paul Brennan; Ros Eeles; Rosemarie Davidson; Adrienne Sexton; Alice Christian; Alison Trainer; Allan Spigelman; Andrew Fellows; Andrew Shelling; Anna De Fazio; Anneke Blackburn; Ashley Crook; Bettina Meiser; Briony Patterson; Christine Clarke; Clare Hunt; Clare Scott; David Amor; Deb Marsh; Edward Edkins; Elizabeth Salisbury; Eric Haan; Eveline Neidermayr; Finlay Macrea; Gelareh Farshid; Geoff Lindeman; Georgia Trench; Graham Mann; Graham Giles; Grantley Gill; Heather Thorne; Ian Hickie; Ingrid Winship; James Flanagan; James Kollias; Jane Visvader; Jessica Taylor; Jo Burke; Jodi Saunus; John Forbes; John Hopper; Juliet French; Kathy Tucker; Kathy Wu; Kelly Phillips; Lara Lipton; Leslie Andrews; Lizz Lobb; Logan Walker; Maira Kentwell; Mandy Spurdle; Margaret Cummings; Margaret Gleeson; Marion Harris; Mark Jenkins; Mary Anne Young; Martin Delatycki; Mathew Wallis; Matthew Burgess; Melanie Price; Melissa Brown; Melissa Southey; Michael Bogwitz; Michael Field; Michael Friedlander; Michael Gattas; Mona Saleh; Nick Hayward; Nick Pachter; Paul Cohen; Pascal Duijf; Paul James; Pete Simpson; Peter Fong; Phyllis Butow; Rachael Williams; Rick Kefford; Rodney Scott; Roger Milne; Rosemary Balleine; SarahJane Dawson; Sheau Lok; Shona O'Connell; Sian Greening; Sophie Nightingale; Stacey Edwards; Stephen Fox; Sue-Anne Mclachlan; Sunil Lakhani; Yoland Antill; Cora Aalfs; Hanne Meijers-Heijboer; Klaartje van Engelen; Hans Gille; Ingrid Boere; Margriet Collee; Carolien van Deurzen; Maartje Hooning; Inge-Marie Obdeijn; Ans van den Ouweland; Caroline Seynaeve; Sabine Siesling; Janneke Verloop; Christi van Asperen; Twiggy van Cronenburg; Rien Blok; Maaike de Boer; Encarna Gomez Garcia; Muriel Adank; Frans Hogervorst; Denise Jenner; Flora van Leeuwen; Matti Rookus; Nicola Russell; Marjanka Schmidt; Sandra van den Belt-Dusebout; Carolien Kets; Arjen Mensenkamp; Truuske de Bock; Annemieke van Der Hout; Marian Mourits; Jan Oosterwijk; Margreet Ausems; Marco Koudijs; Deborah Marsh; Robert Baxter; Desmond Yip; Jane Carpenter; Alison Davis; Nirmala Pathmanathan; Peter Simpson; Dinny Graham; Mythily Sachchithananthan; KConFab Investigators

doi:10.1038/s41588-019-0537-1

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Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes

Journal article

Peer reviewed

Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes

Laura Fachal, Hugues Aschard, Jonathan Beesley, Daniel R. Barnes, Jamie Allen, Siddhartha Kar, Karen A. Pooley, Joe Dennis, Kyriaki Michailidou, Constance Turman, …

Nature genetics, Vol.52(1), pp.56-73

01/01/2020

DOI: https://doi.org/10.1038/s41588-019-0537-1

PMID: 31911677

Abstract

Genetics & Heredity

Life Sciences & Biomedicine

Science & Technology

Fine-mapping of causal variants and integration of epigenetic and chromatin conformation data identify likely target genes for 150 breast cancer risk regions. Genome-wide association studies have identified breast cancer risk variants in over 150 genomic regions, but the mechanisms underlying risk remain largely unknown. These regions were explored by combining association analysis with in silico genomic feature annotations. We defined 205 independent risk-associated signals with the set of credible causal variants in each one. In parallel, we used a Bayesian approach (PAINTOR) that combines genetic association, linkage disequilibrium and enriched genomic features to determine variants with high posterior probabilities of being causal. Potentially causal variants were significantly over-represented in active gene regulatory regions and transcription factor binding sites. We applied our INQUSIT pipeline for prioritizing genes as targets of those potentially causal variants, using gene expression (expression quantitative trait loci), chromatin interaction and functional annotations. Known cancer drivers, transcription factors and genes in the developmental, apoptosis, immune system and DNA integrity checkpoint gene ontology pathways were over-represented among the highest-confidence target genes.

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Title: Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes
Creators - without role: Laura Fachal - University of Cambridge
Hugues Aschard - Institut Pasteur
Jonathan Beesley - QIMR Berghofer Medical Research Institute
Daniel R. Barnes - University of Cambridge
Jamie Allen - University of Cambridge
Siddhartha Kar - University of Cambridge
Karen A. Pooley - University of Cambridge
Joe Dennis - University of Cambridge
Kyriaki Michailidou - University of Cambridge
Constance Turman - Harvard University
Penny Soucy - Centre Hospitalier Universitaire de Québec
Audrey Lemacon - Centre Hospitalier Universitaire de Québec
Michael Lush - University of Cambridge
Jonathan P. Tyrer - University of Cambridge
Maya Ghoussaini - University of Cambridge
Mahdi Moradi Marjaneh - QIMR Berghofer Medical Research Institute
Xia Jiang - Harvard University
Simona Agata - Istituto Oncologico Veneto
Kristiina Aittomaki - University of Helsinki
M. Rosario Alonso - Spanish Natl Canc Res Ctr, Human Genotyping CEGEN Unit, Human Canc Genet Program, Madrid, Spain
Irene L. Andrulis - Lunenfeld-Tanenbaum Research Institute
Hoda Anton-Culver - University of California, Irvine
Natalia N. Antonenkova - N.N. Alexandrov National Cancer Centre
Adalgeir Arason - Reykjavík University
Volker Arndt - German Cancer Research Center
Kristan J. Aronson - Queen's University
Banu K. Arun - The University of Texas MD Anderson Cancer Center
Bernd Auber - Medizinische Hochschule Hannover
Paul L. Auer - University of Wisconsin–Milwaukee
Jacopo Azzollini - Fondazione IRCCS Istituto Nazionale dei Tumori
Judith Balmana - Vall d'Hebron Hospital Universitari
Rosa B. Barkardottir - Reykjavík University
Daniel Barrowdale - University of Cambridge
Alicia Beeghly-Fadiel - Vanderbilt University
Javier Benitez - Centro de Investigación Biomédica en Red
Marina Bermisheva - Ufa Institute of Chemistry
Katarzyna Bialkowska - College Station Medical Center
Amie M. Blanco - Cancer Genetics
Carl Blomqvist - Örebro University Hospital
William Blot - Vanderbilt University
Natalia Bogdanova - N.N. Alexandrov National Cancer Centre
Stig E. Bojesen - University of Copenhagen
Manjeet K. Bolla - University of Cambridge
Bernardo Bonanni - European Institute of Oncology
Ake Borg - Skåne University Hospital
Kristin Bosse - University of Tübingen
Hiltrud Brauch - Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology
Hermann Brenner - German Cancer Research Center
Ignacio Briceno - Pontificia Universidad Javeriana
Ian W. Brock - University of Sheffield
Angela Brooks-Wilson - BC Cancer Agency
Thomas Bruening - Ruhr University Bochum
Barbara Burwinkel - German Cancer Research Center
Saundra S. Buys - Huntsman Cancer Institute
Qiuyin Cai - Vanderbilt University
Trinidad Caldes - Instituto de Investigación Sanitaria del Hospital Clínico San Carlos
Maria A. Caligo - Istituto di Genetica Molecolare
Nicola J. Camp - Huntsman Cancer Institute
Ian Campbell - Peter MacCallum Cancer Centre
Federico Canzian - German Cancer Research Center
Jason S. Carroll - Cancer Research UK Cambridge Center
Brian D. Carter - American Cancer Society
Jose E. Castelao - Servicio Gallego de Salud
Jocelyne Chiquette - Centre Hospitalier Universitaire de Québec
Hans Christiansen - Medizinische Hochschule Hannover
Wendy K. Chung - Columbia University
Kathleen B. M. Claes - Ghent University Hospital
Christine L. Clarke - University of Sydney
J. Margriet Collee - Erasmus MC
Sten Cornelissen - The Netherlands Cancer Institute
Fergus J. Couch - Mayo Clinic
Angela Cox - University of Sheffield
Simon S. Cross - University of Sheffield
Cezary Cybulski - Pomeranian Medical University
Kamila Czene - Karolinska Institutet
Mary B. Daly - Fox Chase Cancer Center
Miguel de la Hoya - Instituto de Investigación Sanitaria del Hospital Clínico San Carlos
Peter Devilee - Leiden University Medical Center
Orland Diez - Vall d'Hebron Hospital Universitari
Yuan Chun Ding - City of Hope
Gillian S. Dite - University of Melbourne
Susan M. Domchek - University of Pennsylvania
Thilo Doerk - Supreme Council Of Health
Isabel dos-Santos-Silva - London School of Hygiene & Tropical Medicine
Arnaud Droit - Centre Hospitalier Universitaire de Québec
Stephane Dubois - Centre Hospitalier Universitaire de Québec
Martine Dumont - Centre Hospitalier Universitaire de Québec
Mercedes Duran - Instituto de Biología y Genética Molecular
Lorraine Durcan - University of Southampton
Miriam Dwek - University of Westminster
Diana M. Eccles - University of Southampton
Christoph Engel - Leipzig University
Mikael Eriksson - Karolinska Institutet
D. Gareth Evans - Manchester Academic Health Science Centre
Peter A. Fasching - University of California, Los Angeles
Olivia Fletcher - Breast Cancer Now
Giuseppe Floris - KU Leuven
Henrik Flyger - Gentofte Hospital
Lenka Foretova - Masaryk Memorial Cancer Institute
William D. Foulkes - McGill University
Eitan Friedman - College Station Medical Center
Lin Fritschi - Curtin University
Debra Frost - University of Cambridge
Marike Gabrielson - Karolinska Institutet
Manuela Gago-Dominguez - College Station Medical Center
Gaetana Gambino - Univ Hosp, SOD Genet Mol, Pisa, Italy
Patricia A. Ganz - Supreme Council Of Health
Susan M. Gapstur - Amer Canc Soc, Behav & Epidemiol Res Grp, Atlanta, GA 30329 USA
Judy Garber - Dana Farber Canc Inst, Canc Risk & Prevent Clin, Boston, MA 02115 USA
Jose A. Garcia-Saenz - Instituto de Investigación Sanitaria del Hospital Clínico San Carlos
Mia M. Gaudet - Amer Canc Soc, Behav & Epidemiol Res Grp, Atlanta, GA 30329 USA
Vassilios Georgoulias - College Station Medical Center
Graham G. Giles - University of Melbourne
Gord Glendon - Lunenfeld-Tanenbaum Research Institute
Andrew K. Godwin - University of Kansas
Mark S. Goldberg - McGill University
David E. Goldgar - University of Utah
Anna Gonzalez-Neira - Spanish Natl Canc Res Ctr CNIO, Human Canc Genet Programme, Madrid, Spain
Maria Grazia Tibiletti - ASST Settelaghi, UO Anat Patol Osped Circolo, Varese, Italy
Mark H. Greene - NCI, Clin Genet Branch, Div Canc Epidemiol & Genet, NIH, Bethesda, MD 20892 USA
Mervi Grip - University of Oulu
Jacek Gronwald - College Station Medical Center
Anne Grundy - Univ Montreal, CHUM, Ctr Rech, Montreal, PQ, Canada
Pascal Guenel - University of Paris-Saclay
Eric Hahnen - University of Cologne
Christopher A. Haiman - Supreme Council Of Health
Niclas Hakansson - Karolinska Institutet
Per Hall - Karolinska Institutet
Ute Hamann - Heidelberg
Patricia A. Harrington - University of Cambridge
Jaana M. Hartikainen - University of Eastern Finland
Mikael Hartman - Supreme Council Of Health
Wei He - Karolinska Institutet
Catherine S. Healey - University of Cambridge
Bernadette A. M. Heemskerk-Gerritsen - Erasmus MC
Jane Heyworth - University of Western Australia
Peter Hillemanns - Supreme Council Of Health
Frans B. L. Hogervorst - Antoni van Leeuwenhoek Hosp, Netherlands Canc Inst, Family Canc Clin, Amsterdam, Netherlands
Antoinette Hollestelle - Erasmus MC
Maartje J. Hooning - Erasmus MC
John L. Hopper - University of Melbourne
Anthony Howell - University of Manchester
Guanmengqian Huang - Heidelberg
Peter J. Hulick - College Station Medical Center
Evgeny N. Imyanitov - NN Petrov Inst Oncol, St Petersburg, Russia
Claudine Isaacs - Georgetown University
Motoki Iwasaki - Natl Canc Ctr, Ctr Publ Hlth Sci, Div Epidemiol, Tokyo, Japan
Agnes Jager - Erasmus MC
Milena Jakimovska - Macedonian Acad Sci & Arts, Res Ctr Genet Engn & Biotechnol Georgi D Efremov, Skopje, North Macedonia
Anna Jakubowska - College Station Medical Center
Paul A. James - University of Melbourne
Ramunas Janavicius - Vilnius University
Rachel C. Jankowitz - University of Pittsburgh
Esther M. John - Stanford University
Nichola Johnson - Inst Canc Res, Breast Canc Now Toby Robins Res Ctr, London, England
Michael E. Jones - Inst Canc Res, Div Genet & Epidemiol, London, England
Arja Jukkola-Vuorinen - Tampere University
Audrey Jung - Heidelberg
Rudolf Kaaks - Heidelberg
Daehee Kang - College Station Medical Center
Pooja Middha Kapoor - Heidelberg
Beth Y. Karlan - Supreme Council Of Health
Renske Keeman - Antoni van Leeuwenhoek Hosp, Netherlands Canc Inst, Div Mol Pathol, Amsterdam, Netherlands
Michael J. Kerin - Supreme Council Of Health
Elza Khusnutdinova - Federal Reserve
Johanna Kiiski - University of Helsinki
Judy Kirk - Weatmead Hosp, Familial Canc Serv, Sydney, NSW, Australia
Cari M. Kitahara - NCI, Radiat Epidemiol Branch, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA
Yon-Dschun Ko - College Station Medical Center
Irene Konstantopoulou - National Centre of Scientific Research "Demokritos"
Veli-Matti Kosma - University of Eastern Finland
Stella Koutros - NCI, Div Canc Epidemiol & Genet, US Dept HHS, NIH, Bethesda, MD 20892 USA
Katerina Kubelka-Sabit - Clin Hosp Acibadem Sistina, Dept Histopathol & Cytol, Skopje, North Macedonia
Ava Kwong - Hong Kong Hereditary Breast Canc Family Registry, Happy Valley, Canc Genet Ctr, Hong Kong, Peoples R China
Kyriacos Kyriacou - Cyprus Institute
Yael Laitman - College Station Medical Center
Diether Lambrechts - VIB, VIB Ctr Canc Biol, Leuven, Belgium
Eunjung Lee - Supreme Council Of Health
Goska Leslie - University of Cambridge
Jenny Lester - Supreme Council Of Health
Fabienne Lesueur - Institute Curie
Annika Lindblom - Karolinska Institutet
Wing-Yee Lo - Fischer
Jirong Long - Vanderbilt University
Artitaya Lophatananon - University of Manchester
Jennifer T. Loud - NCI, Clin Genet Branch, Div Canc Epidemiol & Genet, NIH, Bethesda, MD 20892 USA
Jan Lubinski - College Station Medical Center
Robert J. MacInnis - University of Melbourne
Tom Maishman - University of Southampton
Enes Makalic - University of Melbourne
Arto Mannermaa - University of Eastern Finland
Mehdi Manoochehri - Heidelberg
Siranoush Manoukian - Fdn IRCCS Ist Nazl Tumori Milano, Dept Med Oncol & Hematol, Unit Med Genet, Milan, Italy
Sara Margolin - Soder Sjukhuset, Dept Oncol, Stockholm, Sweden
Maria Elena Martinez - Univ Calif San Diego, Moores Canc Ctr, La Jolla, CA 92093 USA
Keitaro Matsuo - Aichi Canc Ctr, Div Canc Epidemiol & Prevent, Res Inst, Nagoya, Aichi, Japan
Tabea Maurer - Univ Med Ctr Hamburg Eppendorf, Univ Canc Ctr Hamburg, Canc Epidemiol Grp, Hamburg, Germany
Dimitrios Mavroudis - College Station Medical Center
Rebecca Mayes - University of Cambridge
Lesley McGuffog - University of Cambridge
Catriona McLean - The Alfred Hospital
Noura Mebirouk - Institute Curie
Alfons Meindl - Univ Munich, Dept Gynecol & Obstet, Munich, Germany
Austin Miller - Data Management
Nicola Miller - Supreme Council Of Health
Marco Montagna - Veneto Inst Oncol IOV, Immunol & Mol Oncol Unit, IRCCS, Padua, Italy
Fernando Moreno - Instituto de Investigación Sanitaria del Hospital Clínico San Carlos
Kenneth Muir - University of Manchester
Anna Marie Mulligan - University of Toronto
Victor M. Munoz-Garzon - Vigo
Taru A. Muranen - University of Helsinki
Steven A. Narod - University of Toronto
Rami Nassir - Umm al-Qura University
Katherine L. Nathanson - Univ Penn, Basser Ctr BRCA, Abramson Canc Ctr, Philadelphia, PA 19104 USA
Susan L. Neuhausen - Beckman Research Institute
Heli Nevanlinna - University of Helsinki
Patrick Neven - Univ Hosp Leuven, Leuven Multidisciplinary Breast Ctr, Leuven Canc Inst, Dept Oncol, Leuven, Belgium
Finn C. Nielsen - College Station Medical Center
Liene Nikitina-Zake - Riga
Aaron Norman - Mayo Clin, Dept Hlth Sci Res, Rochester, MN USA
Kenneth Offit - Mécanique et Engrenage Moderne
Edith Olah - Natl Inst Oncol, Dept Mol Genet, Budapest, Hungary
Olufunmilayo Olopade - University of Chicago
Hakan Olsson - Lund University
Nick Orr - Queens University
Ana Osorio - Ctr Invest Biomed Red Enfermedades Raras CIBERER, Madrid, Spain
V. Shane Pankratz - Univ New Mexico, Hlth Sci Ctr, Albuquerque, NM 87131 USA
Janos Papp - Natl Inst Oncol, Dept Mol Genet, Budapest, Hungary
Sue K. Park - College Station Medical Center
Tjoung-Won Park-Simon - Supreme Council Of Health
Michael T. Parsons - College Station Medical Center
James Paul - University of Glasgow
Inge Sokilde Pedersen - Aalborg University
Bernard Peissel - Fdn IRCCS Ist Nazl Tumori Milano, Dept Med Oncol & Hematol, Unit Med Genet, Milan, Italy
Beth Peshkin - Georgetown University
Paolo Peterlongo - Inst Mol Oncol, Genome Diagnost Program, IFOM FIRC Italian Fdn Canc Res, Milan, Italy
Julian Peto - Supreme Council Of Health
Dijana Plaseska-Karanfilska - Macedonian Acad Sci & Arts, Res Ctr Genet Engn & Biotechnol Georgi D Efremov, Skopje, North Macedonia
Karolina Prajzendanc - College Station Medical Center
Ross Prentice - Hutchinson
Nadege Presneau - University of Westminster
Darya Prokofyeva - UFA
Miquel Angel Pujana - Biomed Research Institute
Katri Pylkas - University of Oulu
Paolo Radice - Fdn IRCCS Ist Nazl Tumori INT, Dept Res, Unit Mol Bases Genet Risk & Genet Testing, Milan, Italy
Susan J. Ramus - UNSW Sydney
Johanna Rantala - Karolinska Institutet
Rohini Rau-Murthy - Mécanique et Engrenage Moderne
Gad Rennert - Carmel
Harvey A. Risch - Supreme Council Of Health
Mark Robson - Mécanique et Engrenage Moderne
Atocha Romero - College Station Medical Center
Maria Rossing - College Station Medical Center
Emmanouil Saloustros - Univ Hosp Larissa, Dept Oncol, Larisa, Greece
Estela Sanchez-Herrero - College Station Medical Center
Dale P. Sandler - Triangle
Marta Santamarina - Ctr Invest Biomed Red Enfermedades Raras CIBERER, Madrid, Spain
Christobel Saunders - University of Western Australia
Elinor J. Sawyer - Kings Coll London, Guys Hosp, Res Oncol, London, England
Maren T. Scheuner - Univ Calif San Francisco, Canc Genet & Prevent Program, San Francisco, CA 94143 USA
Daniel F. Schmidt - University of Melbourne
Rita K. Schmutzler - University of Cologne
Andreas Schneeweiss - Heidelberg University
Minouk J. Schoemaker - Inst Canc Res, Div Genet & Epidemiol, London, England
Ben Schoettker - Heidelberg
Peter Schuermann - Supreme Council Of Health
Christopher Scott - Mayo Clin, Dept Hlth Sci Res, Rochester, MN USA
Rodney J. Scott - John Hunter Hospital
Leigha Senter - The Ohio State University
Caroline M. Seynaeve - Erasmus MC
Mitul Shah - University of Cambridge
Priyanka Sharma - University of Kansas
Chen-Yang Shen - Acad Sinica, Inst Biomed Sci, Taipei, Taiwan
Xiao-Ou Shu - Vanderbilt University
Christian F. Singer - University of Vienna
Thomas P. Slavin - City Hope Natl Med Ctr, Clin Canc Genom, Duarte, CA USA
Snezhana Smichkoska - College Station Medical Center
Melissa C. Southey - Monash University
John J. Spinelli - BC Canc, Populat Oncol, Vancouver, BC, Canada
Amanda B. Spurdle - College Station Medical Center
Jennifer Stone - University of Melbourne
Dominique Stoppa-Lyonnet - Inserm
Christian Sutter - Heidelberg
Anthony J. Swerdlow - Inst Canc Res, Div Genet & Epidemiol, London, England
Rulla M. Tamimi - Supreme Council Of Health
Yen Yen Tan - University of Vienna
William J. Tapper - University of Southampton
Jack A. Taylor - Triangle
Manuel R. Teixeira - Portuguese Oncol Inst, Dept Genet, Porto, Portugal
Maria Tengstroem - University of Eastern Finland
Soo Hwang Teo - Canc Res Malaysia, Breast Canc Res Programme, Kuala Lumpur, Malaysia
Mary Beth Terry - Columbia University
Alex Teul - Catalan Inst Oncol, CIBERONC, ONCOBELL IDIBELL IDIBGI IGTP, Hereditary Canc Program, Barcelona, Spain
Mads Thomassen - Odense Univ Hosp, Dept Clin Genet, Odence, Denmark
Darcy L. Thull - University of Pittsburgh
Marc Tischkowitz - McGill University
Amanda E. Toland - The Ohio State University
Rob A. E. M. Tollenaar - Leiden University
Ian Tomlinson - University of Birmingham
Diana Torres - Pontificia Univ Javeriana, Inst Human Genet, Bogota, Colombia
Gabriela Torres-Mejia - Natl Inst Publ Hlth, Ctr Populat Hlth Res, Cuernavaca, Morelos, Mexico
Melissa A. Troester - Univ North Carolina Chapel Hill, Dept Epidemiol, Gillings Sch Global Publ Hlth, Chapel Hill, NC USA
Therese Truong - University of Paris-Saclay
Nadine Tung - College Station Medical Center
Maria Tzardi - Univ Hosp Heraklion, Dept Pathol, Iraklion, Greece
Hans-Ulrich Ulmer - Frauenklin Stadtklin Baden Baden, Baden Baden, Germany
Celine M. Vachon - Mayo Clin, Div Epidemiol, Dept Hlth Sci Res, Rochester, MN USA
Christi J. van Asperen - Leiden University
Lizet E. van der Kolk - Antoni van Leeuwenhoek Hosp, Netherlands Canc Inst, Family Canc Clin, Amsterdam, Netherlands
Elizabeth J. van Rensburg - University of Pretoria
Ana Vega - College Station Medical Center
Alessandra Viel - Czech Radio
Joseph Vijai - Mécanique et Engrenage Moderne
Maartje J. Vogel - Antoni van Leeuwenhoek Hosp, Netherlands Canc Inst, Family Canc Clin, Amsterdam, Netherlands
Qin Wang - University of Cambridge
Barbara Wappenschmidt - University of Cologne
Clarice R. Weinberg - Biostat
Jeffrey N. Weitzel - City Hope Natl Med Ctr, Clin Canc Genom, Duarte, CA USA
Camilla Wendt - Karolinska Institutet
Hans Wildiers - Univ Hosp Leuven, Leuven Multidisciplinary Breast Ctr, Leuven Canc Inst, Dept Oncol, Leuven, Belgium
Robert Winqvist - University of Oulu
Alicja Wolk - Karolinska Institutet
Anna H. Wu - Supreme Council Of Health
Drakoulis Yannoukakos - National Centre of Scientific Research "Demokritos"
Yan Zhang - Heidelberg
Wei Zheng - Vanderbilt University
David Hunter - University of Oxford
Paul D. P. Pharoah - University of Cambridge
Jenny Chang-Claude - Heidelberg
Montserrat Garcia-Closas - Inst Canc Res, Div Genet & Epidemiol, London, England
Marjanka K. Schmidt - Antoni van Leeuwenhoek Hosp, Netherlands Canc Inst, Div Mol Pathol, Amsterdam, Netherlands
Roger L. Milne - University of Melbourne
Vessela N. Kristensen - Oslo Univ Hosp, Inst Canc Res, Dept Canc Genet, Radiumhosp, Oslo, Norway
Juliet D. French - College Station Medical Center
Stacey L. Edwards - College Station Medical Center
Antonis C. Antoniou - University of Cambridge
Georgia Chenevix-Trench - College Station Medical Center
Jacques Simard - Université du Québec
Douglas F. Easton - University of Cambridge
Peter Kraft - Supreme Council Of Health
Alison M. Dunning - University of Cambridge
Veronique Mari - Ctr Antoine Lacassagne, Nice, France
Pascaline Berthet - Ctr Francois Baclesse, Caen, France
Laurent Castera - Ctr Francois Baclesse, Caen, France
Dominique Vaur - Ctr Francois Baclesse, Caen, France
Hakima Lallaoui - Ctr Hosp La Rochelle, La Rochelle, France
Yves-Jean Bignon - Ctr Jean Perrin, Clermont Ferrand, France
Nancy Uhrhammer - Ctr Jean Perrin, Clermont Ferrand, France
Valerie Bonadona - Ctr Leon Berard, Lyon, France
Christine Lasset - Ctr Leon Berard, Lyon, France
Francoise Revillion - Ctr Oscar Lambret, Lille, France
Paul Vennin - Ctr Oscar Lambret, Lille, France
Daniele Muller - Ctr Paul Strauss, Strasbourg, France
Denise Molina Gomes - CHI Poissy, Poissy, France
Olivier Ingster - Centre Hospitalier Universitaire d'Angers
Isabelle Coupier - CHU Arnaud de Villeneuve, Montpellier, France
Pascal Pujol - CHU Arnaud de Villeneuve, Montpellier, France
Marie-Agnes Collonge-Rame - CHU Besancon, Besancon, France
Isabelle Mortemousque - CHU Bretonneau, Tours, France
Odile Bera - Fondazione Ricerca Traslazionale
Mickaelle Rose - Fondazione Ricerca Traslazionale
Amandine Baurand - CHU Dijon, Dijon, France
Geoffrey Bertolone - CHU Dijon, Dijon, France
Laurence Faivre - CHU Dijon, Dijon, France
Hlne Dreyfus - CHU Grenoble, Grenoble, France
Dominique Leroux - CHU Grenoble, Grenoble, France
Laurence Venat-Bouvet - CHU Limoges, Limoges, France
Stephane Bezieau - CHU Nantes, Nantes, France
Capucine Delnatte - CHU Nantes, Nantes, France
Jean Chiesa - CHU Nimes Caremeau, Nimes, France
Brigitte Gilbert-Dussardier - Centre Hospitalier Universitaire de Poitiers
Paul Gesta - Centre Hospitalier Universitaire de Poitiers
Fabienne Prieur Prieur - CHU St Etienne, St Etienne, France
Myriam Bronner - CHU Vandoeuvre Les Nancy, Vandoeuvre Les Nancy, France
Johanna Sokolowska - CHU Vandoeuvre Les Nancy, Vandoeuvre Les Nancy, France
Florence Coulet - Grp Hosp Pitie Salpetriere, Paris, France
Nadia Boutry-Kryza - Hosp Civils Lyon, Ctr Leon Berard, Lyon, France
Alain Calender - Hosp Civils Lyon, Ctr Leon Berard, Lyon, France
Sophie Giraud - Hosp Civils Lyon, Ctr Leon Berard, Lyon, France
Melanie Leone - Hosp Civils Lyon, Ctr Leon Berard, Lyon, France
Sandra Fert-Ferrer - Hotel Dieu Ctr Hosp, Chambery, France
Yue Jiao - Mines Paris - PSL
Fabienne Lesueur Lesueur - Mines Paris - PSL
Emmanuelle Barouk-Simonet - Inst Bergonie, Bordeaux, France
Virginie Bubien - Inst Bergonie, Bordeaux, France
Michel Longy - Inst Bergonie, Bordeaux, France
Nicolas Sevenet - Inst Bergonie, Bordeaux, France
Laurence Gladieff - Inst Claudius Regaud, Toulouse, France
Christine Toulas - Inst Claudius Regaud, Toulouse, France
Audrey Reimineras - Institute Paoli-Calmettes
Hagay Sobol - Institute Paoli-Calmettes
Brigitte Bressac-de Paillerets - Gustave Roussy, Serv Genet, Villejuif, France
Odile Cabaret - Gustave Roussy, Serv Genet, Villejuif, France
Olivier Caron - Gustave Roussy, Serv Genet, Villejuif, France
Marine Guillaud-Bataille - Gustave Roussy, Serv Genet, Villejuif, France
Etienne Rouleau - Gustave Roussy, Serv Genet, Villejuif, France
Muriel Belotti - Heidelberg
Bruno Buecher - Heidelberg
Sandrine Caputo - Heidelberg
Chrystelle Colas - Institute Curie
Antoine De Pauw - Heidelberg
Emmanuelle Fourme - Institute Curie
Marion Gauthier-Villars - Heidelberg
Lisa Golmard - Heidelberg
Virginie Moncoutier - Heidelberg
Claire Saule - Heidelberg
Alan Donaldson - Avon
Alex Murray - College Station Medical Center
Angela Brady - North West London Hosp NHS Trust, Kennedy Galton Ctr, North West Thames Reg Genet Serv, Harrow, Middx, England
Carole Brewer - Phillips Exeter Academy
Caroline Pottinger - College Station Medical Center
Clare Miller - Alder
David Gallagher - Mater Private Hosp, Dublin, Ireland
Helen Gregory - University of Aberdeen
Jackie Cook - Sheffield Childrens Hosp, Sheffield Clin Genet Serv, Sheffield, S Yorkshire, England
Jacqueline Eason - Nottingham Univ Hosp NHS Trust, Nottingham Clin Genet Serv, Notingham, England
Julian Adlard - Chapel Allerton Hosp, Yorkshire Reg Genet Serv, Leeds, W Yorkshire, England
Julian Barwell - Univ Hosp Leicester NHS Trust, Leicestershire Clin Genet Serv, Leicester, Leics, England
Kai-Ren Ong - Birmingham Womens Hosp Healthcare NHS Trust, West Midlands Reg Genet Serv, Birmingham, W Midlands, England
Katie Snape - University of London
Lisa Walker - Churchill Hosp, Oxford Reg Genet Serv, Oxford, England
Louise Izatt - Guys & St Thomas NHS Fdn Trust, Clin Genet, London, England
Lucy Side - Princess Anne Hosp, Wessex Clin Genet Serv, Southampton, Hants, England
Mark T. Rogers - College Station Medical Center
Mary E. Porteous - Western Gen Hosp, South East Scotland Reg Genet Serv, Edinburgh, Midlothian, Scotland
Munaza Ahmed - Ormond
Patrick J. Morrison - Northern (Arctic) Federal University
Paul Brennan - College Station Medical Center
Ros Eeles - Inst Canc Res & Royal Marsden NHS Fdn Trust, Oncogenet Team, Sutton, Surrey, England
Rosemarie Davidson - South Glasgow Univ Hosp, Dept Clin Genet, Glasgow, Lanark, Scotland
Adrienne Sexton - Royal Melbourne Hosp, Familial Canc Ctr, Melbourne, Vic, Australia
Alice Christian - Wellington Hosp, Genet Dept, Cent Reg Genet Serv, Wellington, New Zealand
Alison Trainer - Peter MacCallum Canc Ctr, Melbourne, Vic, Australia
Allan Spigelman - St Vincents Hosp, Family Canc Clin, Sydney, NSW, Australia
Andrew Fellows - Peter MacCallum Canc Ctr, Melbourne, Vic, Australia
Andrew Shelling - University of Auckland
Anna De Fazio - Westmead Institute
Anneke Blackburn - University of Canberra
Ashley Crook - Royal North Shore Hosp, Dept Clin Genet, Sydney, NSW, Australia
Bettina Meiser - Uivers New South Wales, Prince Wales Hosp, Sydney, NSW, Australia
Briony Patterson - Royal Hobart Hosp, Clin Genet Serv, Hobart, Tas, Australia
Christine Clarke - University of Sydney
Clare Hunt - College Station Medical Center
Clare Scott - College Station Medical Center
David Amor - Royal Childrens Hosp, Genet Hlth Serv Victoria, Melbourne, Vic, Australia
Deb Marsh - College Station Medical Center
Edward Edkins - Princess Margret Hosp Children, Clin Chem, Perth, WA, Australia
Elizabeth Salisbury - Prince Wales Hosp, Anat Pathol, Sydney, NSW, Australia
Eric Haan - College Station Medical Center
Eveline Neidermayr - Peter MacCallum Canc Ctr, Melbourne, Vic, Australia
Finlay Macrea - Royal Melbourne Hosp, Family Canc Clin, Melbourne, Vic, Australia
Gelareh Farshid - IMVS, SA Tissue Pathol, Adelaide, SA, Australia
Geoff Lindeman - College Station Medical Center
Georgia Trench - College Station Medical Center
Graham Mann - Westmead Institute
Graham Giles - Anticanc Council Victoria, Melbourne, Vic, Australia
Grantley Gill - Royal Adelaide Hosp, Dept Surg, Adelaide, SA, Australia
Heather Thorne - Peter MacCallum Canc Ctr, Melbourne, Vic, Australia
Ian Hickie - Brain & Mind Ctr, Sydney, NSW, Australia
Ingrid Winship - College Station Medical Center
James Flanagan - Imperial Coll, Dept Surg & Oncol, Epigenet Unit, London, England
James Kollias - Royal Adelaide Hosp, Breast Endocrine & Surg Unit, Adelaide, SA, Australia
Jane Visvader - College Station Medical Center
Jessica Taylor - College Station Medical Center
Jo Burke - Royal Hobart Hosp, Hobart, Tas, Australia
Jodi Saunus - University of Queensland
John Forbes - Univ Newcastle, Newcastle Mater Hosp, Surg Oncol, Newcastle, NSW, Australia
John Hopper - Mega
Juliet French - University of Queensland
Kathy Tucker - Prince Wales Hosp, Hered Canc Clin, Sydney, NSW, Australia
Kathy Wu - St Vincents Hosp, Family Canc Clin, Sydney, NSW, Australia
Kelly Phillips - College Station Medical Center
Lara Lipton - College Station Medical Center
Leslie Andrews - Prince Wales Hosp, Hereditary Canc Clin, Sydney, NSW, Australia
Lizz Lobb - University of Notre Dame
Logan Walker - University of Otago
Maira Kentwell - Royal Melbourne Hosp, Family Canc Clin, Melbourne, Vic, Australia
Mandy Spurdle - College Station Medical Center
Margaret Cummings - University of Queensland
Margaret Gleeson - Hunter Family Canc Serv, Sydney, NSW, Australia
Marion Harris - College Station Medical Center
Mark Jenkins - University of Melbourne
Mary Anne Young - College Station Medical Center
Martin Delatycki - Royal Childrens Hosp, Genet Hlth Serv Victoria, Melbourne, Vic, Australia
Mathew Wallis - Austin Hlth, Family Canc Clin, Melbourne, Vic, Australia
Matthew Burgess - Austin Hlth, Clin Genet Serv, Melbourne, Vic, Australia
Melanie Price - University of Sydney
Melissa Brown - University of Queensland
Melissa Southey - University of Melbourne
Michael Bogwitz - Royal Melbourne Hosp, Familial Canc Ctr, Melbourne, Vic, Australia
Michael Field - Royal North Shore Hosp, Clin Genet, Sydney, NSW, Australia
Michael Friedlander - College Station Medical Center
Michael Gattas - Royal Childrens Hosp, Queensland Clin Genet Serv, Brisbane, Qld, Australia
Mona Saleh - Prince Wales Hosp, Ctr Genet Educ, Sydney, NSW, Australia
Nick Hayward - College Station Medical Center
Nick Pachter - Mécanique et Engrenage Moderne
Paul Cohen - St John God Subiaco Hosp, Gynaecol Canc Res, Perth, WA, Australia
Pascal Duijf - University of Queensland
Paul James - Peter MacCallum Canc Ctr, Family Canc Clin, Melbourne, Vic, Australia
Pete Simpson - University of Queensland
Peter Fong - Auckland City Hosp, Reg Canc & Blood Serv, Auckland, New Zealand
Phyllis Butow - The Alfred Hospital
Rachael Williams - St Vincents Hosp, Family Canc Clin, Sydney, NSW, Australia
Rick Kefford - College Station Medical Center
Rodney Scott - John Hunter Hospital
Roger Milne - Anticanc Council Victoria, Melbourne, Vic, Australia
Rosemary Balleine - College Station Medical Center
SarahJane Dawson - Peter MacCallum Canc Ctr, Melbourne, Vic, Australia
Sheau Lok - College Station Medical Center
Shona O'Connell - Southern Hlth Familial Canc Ctr, Melbourne, Vic, Australia
Sian Greening - Wollongong Hosp, Illawarra Canc Ctr, Wollongong, NSW, Australia
Sophie Nightingale - Peter MacCallum Canc Ctr, Melbourne, Vic, Australia
Stacey Edwards - College Station Medical Center
Stephen Fox - Peter MacCallum Canc Ctr, Pathol Dept, VCCC Bldg, Melbourne, Vic, Australia
Sue-Anne Mclachlan - St Vincents Hosp, Dept Oncol, Melbourne, Vic, Australia
Sunil Lakhani - University of Queensland
Yoland Antill - Cabrini Hosp, Family Canc Clin, Melbourne, Vic, Australia
Cora Aalfs - College Station Medical Center
Hanne Meijers-Heijboer - University of Amsterdam
Klaartje van Engelen - College Station Medical Center
Hans Gille - University of Amsterdam
Ingrid Boere - Erasmus MC
Margriet Collee - College Station Medical Center
Carolien van Deurzen - College Station Medical Center
Maartje Hooning - Erasmus MC
Inge-Marie Obdeijn - College Station Medical Center
Ans van den Ouweland - College Station Medical Center
Caroline Seynaeve - Erasmus MC
Sabine Siesling - Netherlands Comprehens Canc Org IKNL, Utrecht, Netherlands
Janneke Verloop - Netherlands Comprehens Canc Org IKNL, Utrecht, Netherlands
Christi van Asperen - Leiden University
Twiggy van Cronenburg - Leiden University
Rien Blok - Maastricht University
Maaike de Boer - Maastricht University
Encarna Gomez Garcia - Maastricht University
Muriel Adank - Netherlands Canc Inst, Family Canc Clin, Amsterdam, Netherlands
Frans Hogervorst - Netherlands Canc Inst, Family Canc Clin, Amsterdam, Netherlands
Denise Jenner - Netherlands Canc Inst, Dept Epidemiol, Amsterdam, Netherlands
Flora van Leeuwen - Netherlands Canc Inst, Dept Epidemiol, Amsterdam, Netherlands
Matti Rookus - Netherlands Canc Inst, Dept Epidemiol, Amsterdam, Netherlands
Nicola Russell - Netherlands Canc Inst, Dept Radiotherapy, Amsterdam, Netherlands
Marjanka Schmidt - Netherlands Canc Inst, Div Psychosocial Res & Epidemiol, Amsterdam, Netherlands
Sandra van den Belt-Dusebout - Nationwide Network, Houten, Netherlands
Carolien Kets - Radboud University Nijmegen
Arjen Mensenkamp - Radboud University Nijmegen
Truuske de Bock - University of Groningen
Annemieke van Der Hout - College Station Medical Center
Marian Mourits - University of Groningen
Jan Oosterwijk - College Station Medical Center
Margreet Ausems - College Station Medical Center
Marco Koudijs - College Station Medical Center
Deborah Marsh - University of Technology Sydney
Robert Baxter - University of Sydney
Desmond Yip - University of Canberra
Jane Carpenter - University of Sydney
Alison Davis - University of Canberra
Nirmala Pathmanathan - Western Sydney Local Hlth Dist, Westmead Breast Canc Inst, Sydney, NSW, Australia
Peter Simpson - University of Queensland
Dinny Graham - University of Sydney
Mythily Sachchithananthan - University of Sydney
KConFab Investigators
Publication Details: Nature genetics, Vol.52(1), pp.56-73
Publisher: NATURE PORTFOLIO
Number of pages: 18
Grant note: PERSPECTIVE project (Quebec Breast Cancer Foundation) ZIACP010144 / NATIONAL CANCER INSTITUTE; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Cancer Institute (NCI) PERSPECTIVE project ('Ministere de l'Economie de la Science et de l'Innovation du Quebec' (Genome Quebec) HEALTH-F2-2009-223175; 633784; 634935 / European Union; European Commission; Spanish Government 223175 (HEALTH-F2-2009-223175) / European Community; European Commission NCI Genetic Associations and Mechanisms in Oncology (GAME-ON) initiative ZIAES044005; ZIAES049033; ZIAES102245 / NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Environmental Health Sciences (NIEHS) PSR-SIIRI-701 / Ministry of Economic Development, Innovation and Export Trade of Quebec PERSPECTIVE project (Government of Canada through Canadian Institutes of Health Research); Canadian Institutes of Health Research (CIHR) MC_PC_14105 / MRC; UK Research & Innovation (UKRI); Medical Research Council UK (MRC) 656144 / European Union's Horizon 2020 Research and Innovation Programme under Marie Sklodowska-Curie grant; Marie Curie Actions U19 CA 148065 / NIH Cancer Post-Cancer GWAS initiative grant; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA PERSPECTIVE project (Government of Canada through Genome Canada) C1287/A10118; C8197/A16565; C1287/A16563; C1287/A10710 / Cancer Research UK U19 CA148065; X01HG007492 / Discovery, Biology and Risk of Inherited Variants in Breast Cancer (DRIVE) project (NIH); United States Department of Health & Human Services; National Institutes of Health (NIH) - USA Canadian Institutes of Health Research; Canadian Institutes of Health Research (CIHR)
Identifiers: 9931517608331
Academic Unit: Umm Al Qura University
Language: English
Resource Type: Journal article