Abstract
A total of twenty-eight flavonol glycosides and one alkaloidal metabolite have been detected in 40% MeOH portion after eluting the crude extract from the aerial parts of Bassia eriophora on C-18 short col-umn. These compounds were tentatively detected by using LC-ESI-MS/MS in negative ion mode [M-H]- and represented two major categories: acylated and non-acylated flavonol glycosides. Obtained data indi-cated that Bassia eriophora is a rich new source of flavonol glycosides. Selected compounds were studied by DFT and TD-DFT calculations to determine their physico-chemical properties and their antioxidant ac-tivity. B. eriophora exhibited high TAC, RP and DPPH radical scavenging activity with IC50 of 177.8 mu g/mL. Moreover, reducing power at 5 mu g/ml and TAC at 5 mu g/ml of B. eriophora showed a positive correlation with total flavonoids. The present results may open an avenue to exploit B. eriophora in pharmaceutical applications. (C) 2021 Elsevier B.V. All rights reserved.