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From competition to cooperation: a highly efficient strategy towards well-defined (co)polypeptides
Journal article   Peer reviewed

From competition to cooperation: a highly efficient strategy towards well-defined (co)polypeptides

Wei Zhao, Yves Gnanou and Nikos Hadjichristidis
Chemical communications (Cambridge, England), Vol.51(17), pp.3663-3666
28/02/2015
PMID: 25643829

Abstract

Chemistry Chemistry, Multidisciplinary Physical Sciences Science & Technology
By associating primary (slow but controlled ring-opening polymerization; ROP) and tertiary (fast but uncontrolled ROP) amines in the same molecule, a novel highly active organocatalytic system proceeding by an accelerated amine mechanism through monomer activation (AAMMA) and leading to living ROP of alpha-amino acid N-carboxy-anhydrides at room temperature was successfully developed.

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