Abstract
Two new megastigmane glycosides (
1 and
2) and two new flavone glycosides (
3 and
4) were isolated from the methanol extract of the whole plant of
Caralluma negevensis Zohary (Asclepiadaceae). The structures of the isolated compounds were characterized as (9
R)-2β,9-dihydroxymegastigma-4,7-dien-3-one-9-
O-α-
l-rhamnopyranosyl-(1→6)-β-
d-glucopyranoside (
1), 2β,9-dihydroxymegastigma-4-en-3-one 9-
O-α-
l-rhamnopyranosyl-(1→6)-β-
d-glucopyranoside (
2), luteolin 3′-
O-β-
d-glucopyranoside-4′-
O-α-
l-rhamnopyranosyl-(1→2)-β-
d-glucopyranoside (
3), and luteolin 3′,4′-di-
O-β-
d-glucopyranoside (
4). The structures of the isolated compounds were established on the basis of spectral evidence and chemical transformation.
Two new megastigmane glycosides (
1 and
2) and two new flavone glycosides were isolated from the methanol extract of the whole plant of
Caralluma negevensis Zohary (Asclepiadaceae). The structures of the isolated compounds were established by different spectroscopic methods.