Abstract
To supplement the results of thermal resistance of bovine parvovirus (Haden strain, BPV) published previously, we carried out assays at 60°C (moist heat) to compare the thermal resistance of BPV with that of hepatitis B-virus (HBV). What we know about the resistance of HBV at a temperature of 60°C is mainly based on data collected within the context of blood product pasteurization. The results suggest that at a temperature of 60°C, BPV shows thermal resistance comparable to HBV. Thus, BPV- which is easier to handle- can be considered a good test virus to verify the efficacy of thermal disinfection techniques against HBV.
BPV is very resistant against dry heat of 100°C, the inactivation largely depending upon the residual moisture of the lyophilisate. Reducing the residual moisture from 2% to less than 1%, the exposure time has to be prolonged by ca. 2.5 times to achieve the same virucidal effect.