Abstract
Introduction: Antifungals are used to treat different fungal infections which affect different body part. Systemic antifungals may result in many adverse effects especially gastrointestinal adverse effects. The Aim of these study is to illustrate the common and serious adverse effects of antifungals on gastrointestinal system.
Methodology: contains 3 parts, searching Micromedex, searching the Web of Science and searching Cochrane library for the adverse effects of antifungals.
Results and Discussion: The majority of the gastrointestinal adverse effects aren't serious such as nausea and vomiting, the only serious adverse effects results by systemic antifungals are gastrointestinal hemorrhage and pancreatitis.
Conclusion
There are many common and serious adverse effects for antifungals. Clinicians should exclude the use of drugs associated with common or fatal adverse effects because numerous therapeutic alternatives exist for almost all potential infections.