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Gene-environment interactions in heavy metal and pesticide carcinogenesis
Journal article   Peer reviewed

Gene-environment interactions in heavy metal and pesticide carcinogenesis

Shams Tabrez, Medha Priyadarshini, Shubha Priyamvada, Mohd Shahnawaz Khan, N. A. Arivarasu and Syed Kashif Zaidi
Mutation research. Genetic toxicology and environmental mutagenesis, Vol.760, pp.1-9
15/01/2014
DOI: https://doi.org/10.1016/j.mrgentox.2013.11.002
PMID: 24309507

Abstract

Biotechnology & Applied Microbiology Genetics & Heredity Life Sciences & Biomedicine Science & Technology Toxicology
Cancer is a complex disease involving a sequence of gene-environment interactions. Lifestyle, genetics, dietary factors, and environmental pollutants can increase the risk of cancer. Gene-environment interactions have been studied by a candidate-gene approach focusing on metabolism, DNA repair, and apoptosis. Here, we review the influence of gene-environment interactions in carcinogenesis, with emphasis on heavy metal and pesticide exposures. (C) 2013 Elsevier B.V. All rights reserved.

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