Abstract
In this paper we will introduce a sequence of complex numbers that are called the Jacobi numbers. This sequence generalizes in a natural way several sequences that are known in the literature, such as Catalan numbers, central binomial numbers, generalized catalan numbers, the coefficient of the Hilbert matrix and others. Subsequently, using a study of the polynomial of Jacobi, we give an evaluation of the Hankel determinants that associated with the sequence of Jacobi numbers. Finally, by finding a relationship between the Jacobi numbers and generalized harmonic numbers, we determine the evaluation of the Hankel determinants that are associated with generalized harmonic numbers.