Abstract
The objective of this paper is to investigate the validity conditions for the generalized second law of thermodynamics, and the universal relations for multi-horizon dynamical spacetime. It is found that there are three horizons of McVittie universe termed as event horizon, cosmological apparent horizon, and virtual horizon. The mass-dependent and mass-independent area product relations are formulated in terms of areas of the dynamical event horizon, cosmological horizon and virtual horizon. It is noted that whereas the area sum relation is mass independent, the area product relation is explicitly mass dependent. Moreover, we have also analyzed and listed explicit mass-independent and mass-dependent relations.