Global mortality from dementia: Application of a new method and results from the Global Burden of Disease Study 2019

Emma Nichols; Foad Abd-Allah; Amir Abdoli; Akine Eshete Abosetugn; Woldu Aberhe Abrha; Ahmed Abualhasan; Eman Abu-Gharbieh; Rufus Olusola Akinyemi; Fares Alahdab; Fahad Mash-Hour Alanezi; Vahid Alipour; Iman Ansari; Jalal Arabloo; Amir Ashraf-Ganjouei; Abolfazl Avan; Getinet Ayano; Zaheer-Ud-Din Babar; Atif Amin Baig; Maciej Banach; Miguel A. Barboza; Suzanne Lyn Barker-Collo; Bernhard T. Baune; Akshaya Srikanth Bhagavathula; Krittika Bhattacharyya; Ali Bijani; Antonio Biondi; Tsegaye Adane Birhan; Atanu Biswas; Srinivasa Rao Bolla; Archith Boloor; Carol Brayne; Hermann Brenner; Katrin Burkart; Richard A. Burns; Sharath Burugina Nagaraja; Felix Carvalho; Luis F. S. Castro-de-Araujo; Ferran Catala-Lopez; Ester Cerin; Achille Cernigliaro; Nico-Las Cherbuin; Jee-Young Jasmine Choi; Dinh-Toi Chu; Baye Dagnew; Xiaochen Dai; Lalit Dandona; Rakhi Dandona; Daniel Diaz; Zahra Sadat Dibaji Forooshani; Abdel Douiri; Bruce B. Duncan; David Edvardsson; Shaimaa I. El-Jaafary; Khalil Eskandari; Sharareh Eskandarieh; Valery L. Feigin; Seyed-Mohammad Fereshtehnejad; Eduarda Fernandes; Pietro Ferrara; Irina Filip; Florian Fischer; Shilpa Gaidhane; Kidane Zereabruk Gebregzabiher; Ahmad Ghashghaee; Asadollah Gholamian; Elena V. Gnedovskaya; Mahaveer Golechha; Rajeev Gupta; Vladimir Hachinski; Samer Hamidi; Graeme J. Hankey; Josep Maria Haro; Amr Hassan; Simon I. Hay; Golnaz Heidari; Reza Heidari-Soureshjani; Mowafa Househ; Rabia Hussain; Bing-Fang Hwang; Irena M. Ilic; Milena D. Ilic; Seyed Sina Naghibi Irvani; Hiroyasu Iso; Masao Iwagami; Ravi Prakash Jha; Rizwan Kalani; Himal Kandel; Andre Karch; Ayele Semachew Kasa; Andre Pascal Kengne; Young-Eun Kim; Yun Jin Kim; Sezer Kisa; Adnan Kisa; Mika Kivimaki; Hamidreza Komaki; Ai Koyanagi; Walter A. Kukull; G. Anil Kumar; Manasi Kumar; Ivan Landires; Matilde Leonardi; Stephen S. Lim; Xuefeng Liu; Giancarlo Logroscino; Alan D. Lopez; Stefan Lorkowski; Clement T. Loy; Hawraz Ibrahim M. Amin; Navid Manafi; Narayana Manjunatha; Man Mohan Mehndiratta; Ritesh G. Menezes; Atte Meretoja; Alexander Merkin; Workua Mekonnen Metekiya; Awoke Temesgen Misganaw; Bahram Mohajer; Norlinah Mohamed Ibrahim; Yousef Mohammad; Archisman Mohapatra; Farnam Mohebi; Ali H. Mokdad; Stefania Mondello; Tilahun Belete Mossie; Anwar Mulugeta; Gabriele Nagel; Muhammad Naveed; Vinod C. Nayak; Sandhya Neupane Kandel; Son Hoang Nguyen; Huong Lan Thi Nguyen; Virginia Nunez-Samudio; Felix Akpojene Ogbo; Andrew T. Olagunju; Hans Orru; Sergej M. Ostojic; Samuel M. Ostroff; Nikita Otstavnov; Stanislav S. Otstavnov; Mayowa O. Owolabi; Mona Pathak; Hamidreza Pazoki Toroudi; Carrie B. Peterson; Hai Quang Pham; Michael R. Phillips; Michael A. Piradov; Faheem Hyder Pottoo; Sergio I. Prada; Dimas Ria Angga Pribadi; Amir Radfar; Alberto Raggi; Fakher Rahim; Pradhum Ram; Juwel Rana; Vahid Rashedi; Salman Rawaf; David Laith Rawaf; Nickolas Reinig; Nima Rezaei; Stephen R. Robinson; Michele Romoli; Perminder S. Sachdev; Ramesh Sahathevan; Amirhossein Sahebkar; Mohammad Ali Sahraian; Davide Sattin; Mete Saylan; Mehdi Sayyah; Silvia Schiavolin; Maria Ines Schmidt; Izza Shahid; Masood Ali Shaikh; Mika Shigematsu; Jae Il Shin; Rahman Shiri; Tariq Jamal Siddiqi; Joao Pedro Silva; Jasvinder A. Singh; Amin Soheili; Emma Elizabeth Spurlock; Cassandra E. I. Szoeke; Rafael Tabares-Seisdedos; Biruk Wogayehu Taddele; Bhaskar Thakur; Akhil Soman ThekkePurakkal; Marcos Roberto Tovani-Palone; Bach Xuan Tran; Ravensara S. Travillian; Manjari Tripathi; Gebiyaw Wudie Tsegaye; Muhammad Shariq Usman; Marco Vacante; Diana Zuleika Velazquez; Narayanaswamy Venketasubramanian; Simone Vidale; Vasily Vlassov; Yuan-Pang Wang; Jingkai Wei; Jordan Weiss; Abrha Hailay Weldemariam; Anders Wimo; Chenkai Wu; Ali Yadollahpour; Kazumasa Yamagishi; Yordanos Gizachew Yeshitila; Naohiro Yonemoto; Siddhesh Zadey; Zhi-Jiang Zhang; Christopher J. L. Murray; Theo Vos; GBD 2019 Collaborators

doi:10.1002/trc2.12200

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Global mortality from dementia: Application of a new method and results from the Global Burden of Disease Study 2019

Journal article

Peer reviewed

Global mortality from dementia: Application of a new method and results from the Global Burden of Disease Study 2019

Emma Nichols, Foad Abd-Allah, Amir Abdoli, Akine Eshete Abosetugn, Woldu Aberhe Abrha, Ahmed Abualhasan, Eman Abu-Gharbieh, Rufus Olusola Akinyemi, Fares Alahdab, Fahad Mash-Hour Alanezi, …

Alzheimer's & dementia : translational research & clinical interventions, Vol.7(1), pp.e12200-n/a

2021

DOI: https://doi.org/10.1002/trc2.12200

PMID: 34337138

Abstract

Clinical Neurology

Life Sciences & Biomedicine

Neurosciences

Neurosciences & Neurology

Science & Technology

Introduction Dementia is currently one of the leading causes of mortality globally, and mortality due to dementia will likely increase in the future along with corresponding increases in population growth and population aging. However, large inconsistencies in coding practices in vital registration systems over time and between countries complicate the estimation of global dementia mortality. Methods We meta-analyzed the excess risk of death in those with dementia and multiplied these estimates by the proportion of dementia deaths occurring in those with severe, end-stage disease to calculate the total number of deaths that could be attributed to dementia. Results We estimated that there were 1.62 million (95% uncertainty interval [UI]: 0.41-4.21) deaths globally due to dementia in 2019. More dementia deaths occurred in women (1.06 million [0.27-2.71]) than men (0.56 million [0.14-1.51]), largely but not entirely due to the higher life expectancy in women (age-standardized female-to-male ratio 1.19 [1.10-1.26]). Due to population aging, there was a large increase in all-age mortality rates from dementia between 1990 and 2019 (100.1% [89.1-117.5]). In 2019, deaths due to dementia ranked seventh globally in all ages and fourth among individuals 70 and older compared to deaths from other diseases estimated in the Global Burden of Disease (GBD) study. Discussion Mortality due to dementia represents a substantial global burden, and is expected to continue to grow into the future as an older, aging population expands globally.

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Title: Global mortality from dementia: Application of a new method and results from the Global Burden of Disease Study 2019
Creators - without role: Emma Nichols - Inst Hlth Metr & Evaluat, 3980 15th Ave NE, Seattle, WA 98105 USA
Foad Abd-Allah - Cairo University
Amir Abdoli - Jahrom University
Akine Eshete Abosetugn - Debre Berhan University
Woldu Aberhe Abrha - Aksum University
Ahmed Abualhasan - Cairo University
Eman Abu-Gharbieh - University of Sharjah
Rufus Olusola Akinyemi - University of Ibadan
Fares Alahdab - Evidence
Fahad Mash-Hour Alanezi - Imam Abdulrahman Bin Faisal University
Vahid Alipour - College Station Medical Center
Iman Ansari - Shahed University
Jalal Arabloo - College Station Medical Center
Amir Ashraf-Ganjouei - University of Tehran
Abolfazl Avan - College Station Medical Center
Getinet Ayano - Curtin University
Zaheer-Ud-Din Babar - University of Huddersfield
Atif Amin Baig - Sultan Zainal Abidin University
Maciej Banach - College Station Medical Center
Miguel A. Barboza - Costa Rican Dept Social Secur, Dept Neurosci, San Jose, Costa Rica
Suzanne Lyn Barker-Collo - University of Auckland
Bernhard T. Baune - University of Münster
Akshaya Srikanth Bhagavathula - Charles University
Krittika Bhattacharyya - Natl Inst Biomed Genom, Dept Stat & Computat Genom, Kalyani, W Bengal, India
Ali Bijani - College Station Medical Center
Antonio Biondi - University of Catania
Tsegaye Adane Birhan - University of Gondar
Atanu Biswas - College Station Medical Center
Srinivasa Rao Bolla - Nazarbayev University
Archith Boloor - College Station Medical Center
Carol Brayne - University of Cambridge
Hermann Brenner - Heidelberg
Katrin Burkart - University of Washington
Richard A. Burns - Supreme Council Of Health
Sharath Burugina Nagaraja - College Station Medical Center
Felix Carvalho - Universidade do Porto
Luis F. S. Castro-de-Araujo - University of Melbourne
Ferran Catala-Lopez - Supreme Council Of Health
Ester Cerin - Australian Catholic University
Achille Cernigliaro - Sicilian Reg Hlth Author, Reg Epidemiol Observ Dept, Palermo, Italy
Nico-Las Cherbuin - Supreme Council Of Health
Jee-Young Jasmine Choi - Seoul Natl Univ Hosp, Biomed Informat, Seoul, South Korea
Dinh-Toi Chu - Hanoi Natl Univ Educ, Fac Biol, Hanoi, Vietnam
Baye Dagnew - University of Gondar
Xiaochen Dai - University of Washington
Lalit Dandona - University of Washington
Rakhi Dandona - University of Washington
Daniel Diaz - Univ Nacl Autonoma Mexico, Ctr Complex Sci, Mexico City, DF, Mexico
Zahra Sadat Dibaji Forooshani - University of Tehran
Abdel Douiri - Supreme Council Of Health
Bruce B. Duncan - Univ Fed Rio Grande do Sul, Postgrad Programin Epidemiol, Porto Alegre, RS, Brazil
David Edvardsson - La Trobe University
Shaimaa I. El-Jaafary - Cairo University
Khalil Eskandari - College Station Medical Center
Sharareh Eskandarieh - University of Tehran
Valery L. Feigin - University of Washington
Seyed-Mohammad Fereshtehnejad - Karolinska Institutet
Eduarda Fernandes - Universidade do Porto
Pietro Ferrara - University of Milano-Bicocca
Irina Filip - Kaiser Permanente
Florian Fischer - Ravensburg Weingarten Univ Appl Sci, Inst Gerontol Hlth Serv & Nursing Res, Weingarten, Germany
Shilpa Gaidhane - College Station Medical Center
Kidane Zereabruk Gebregzabiher - Aksum University
Ahmad Ghashghaee - College Station Medical Center
Asadollah Gholamian - Islamic Azad University, Tehran
Elena V. Gnedovskaya - Res Ctr Neurol, Dept Neurol, Moscow, Russia
Mahaveer Golechha - Indian Inst Publ Hlth Gandhinagar, Hlth Syst & Policy Res, Gandhinagar, India
Rajeev Gupta - Eternal Heart Care Ctr & Res Inst, Dept Prevent Cardiol, Jaipur, Rajasthan, India
Vladimir Hachinski - Western University
Samer Hamidi - Hamdan Bin Mohammed Smart University
Graeme J. Hankey - University of Western Australia
Josep Maria Haro - Universitat de Barcelona
Amr Hassan - Cairo University
Simon I. Hay - University of Washington
Golnaz Heidari
Reza Heidari-Soureshjani - University of Tehran
Mowafa Househ - Hamad bin Khalifa University
Rabia Hussain - Supreme Council Of Health
Bing-Fang Hwang - College Station Medical Center
Irena M. Ilic - University of Belgrade
Milena D. Ilic - University of Kragujevac
Seyed Sina Naghibi Irvani - Shahid Beheshti University
Hiroyasu Iso - Osaka University
Masao Iwagami - University of Tsukuba
Ravi Prakash Jha - College Station Medical Center
Rizwan Kalani - University of Washington
Himal Kandel - University of Sydney
Andre Karch - University of Münster
Ayele Semachew Kasa - Bahir Dar University
Andre Pascal Kengne - College Station Medical Center
Young-Eun Kim - Natl Hlth Insurance Serv, Big Data Dept, Wonju, South Korea
Yun Jin Kim - Xiamen University Malaysia
Sezer Kisa - Oslo Metropolitan Univ, Dept Nursing & Hlth Promot, Oslo, Norway
Adnan Kisa - Supreme Council Of Health
Mika Kivimaki - UCL, Dept Epidemiol & Publ Hlth, London, England
Hamidreza Komaki - College Station Medical Center
Ai Koyanagi - CIBERSAM, San Juan Dios Sanit Pk, St Boi De Llobregat, Spain
Walter A. Kukull - University of Washington
G. Anil Kumar - Publ Hlth Fdn India, Gurugram, India
Manasi Kumar - University of Nairobi
Ivan Landires - College Station Medical Center
Matilde Leonardi - Carlo Besta Neurol Inst IRCCS, Neurol Publ Hlth & Disabil Unit, Milan, Italy
Stephen S. Lim - University of Washington
Xuefeng Liu - Univ Michigan, Dept Syst Populat & Leadership, Ann Arbor, MI 48109 USA
Giancarlo Logroscino - University of Bari Aldo Moro
Alan D. Lopez - University of Washington
Stefan Lorkowski - Friedrich Schiller University Jena
Clement T. Loy - University of Sydney
Hawraz Ibrahim M. Amin - Univ Piemonte Orientale, Dept Pharmaceut Sci, Novara, Italy
Navid Manafi - Supreme Council Of Health
Narayana Manjunatha - Natl Inst Mental Hlth & Neurosci, Dept Psychiat, Bengalore, India
Man Mohan Mehndiratta - Janakpuri Super Specialty Hosp Soc, Neurol Dept, New Delhi, India
Ritesh G. Menezes - Imam Abdulrahman Bin Faisal University
Atte Meretoja - Helsinki Univ Hosp, Neurol Unit, Helsinki, Finland
Alexander Merkin - Auckland University of Technology
Workua Mekonnen Metekiya - Mekelle University
Awoke Temesgen Misganaw - University of Washington
Bahram Mohajer - University of Tehran
Norlinah Mohamed Ibrahim - College Station Medical Center
Yousef Mohammad - King Saud University
Archisman Mohapatra - GRID Council, Epidemiol Dept, Bhubaneswar, India
Farnam Mohebi - University of Tehran
Ali H. Mokdad - University of Washington
Stefania Mondello - Messina Univ, Dept Biomed & Dent Sci & Morphofunct Imaging, Messina, Italy
Tilahun Belete Mossie - Bahir Dar University
Anwar Mulugeta - University of South Australia
Gabriele Nagel - College Station Medical Center
Muhammad Naveed - Univ Cent Punjab, Dept Biotechnol, Lahore, Pakistan
Vinod C. Nayak - College Station Medical Center
Sandhya Neupane Kandel - Bupa
Son Hoang Nguyen - Trường ĐH Nguyễn Tất Thành
Huong Lan Thi Nguyen - Duy Tan University
Virginia Nunez-Samudio - Minist Hlth, Herrera, Panama
Felix Akpojene Ogbo - Western Sydney University
Andrew T. Olagunju - McMaster University
Hans Orru - University of Tartu
Sergej M. Ostojic - University of Novi Sad
Samuel M. Ostroff - University of Washington
Nikita Otstavnov - Moscow Inst Phys & Technol, Lab Publ Hlth Indicators Anal & Hlth Digitalizat, Dolgoprudnyi, Russia
Stanislav S. Otstavnov - Moscow Inst Phys & Technol, Lab Publ Hlth Indicators Anal & Hlth Digitalizat, Dolgoprudnyi, Russia
Mayowa O. Owolabi - University of Ibadan
Mona Pathak - College Station Medical Center
Hamidreza Pazoki Toroudi - College Station Medical Center
Carrie B. Peterson
Hai Quang Pham - Duy Tan University
Michael R. Phillips - Shanghai Jiao Tong University
Michael A. Piradov - Res Ctr Neurol, Moscow, Russia
Faheem Hyder Pottoo - Imam Abdulrahman Bin Faisal University
Sergio I. Prada - Valle Lili Fdn, Clin Res Ctr, Cali, Colombia
Dimas Ria Angga Pribadi - Muhammadiyah University of Surakarta
Amir Radfar - College Station Medical Center
Alberto Raggi - Carlo Besta Neurol Inst IRCCS, Neurol Publ Hlth & Disabil Unit, Milan, Italy
Fakher Rahim - College Station Medical Center
Pradhum Ram - Emory University
Juwel Rana - North South Univ, Dept Publ Hlth, Dhaka, Bangladesh
Vahid Rashedi - College Station Medical Center
Salman Rawaf - Imperial Coll London, Dept Primary Care & Publ Hlth, London, England
David Laith Rawaf - Imperial Coll London, WHO Collaborating Ctr Publ Hlth Educ & Training, London, England
Nickolas Reinig - University of Washington
Nima Rezaei - University of Tehran
Stephen R. Robinson - RMIT University
Michele Romoli - University of Perugia
Perminder S. Sachdev - UNSW Sydney
Ramesh Sahathevan - University of Melbourne
Amirhossein Sahebkar - Food & Drug Adm Islamic Republ Iran, Halal Res Ctr IRI, Tehran, Iran
Mohammad Ali Sahraian - University of Tehran
Davide Sattin - Carlo Besta Neurol Inst IRCCS, Neurol Publ Hlth & Disabil Unit, Milan, Italy
Mete Saylan - Bayer, Market Access, Istanbul, Turkey
Mehdi Sayyah - College Station Medical Center
Silvia Schiavolin - Carlo Besta Neurol Inst IRCCS, Neurol Publ Hlth & Disabil Unit, Milan, Italy
Maria Ines Schmidt - Univ Fed Rio Grande do Sul, Postgrad Programin Epidemiol, Porto Alegre, RS, Brazil
Izza Shahid - Ziauddin University
Masood Ali Shaikh
Mika Shigematsu - Natl Inst Infect Dis, Tokyo, Japan
Jae Il Shin - Yonsei University
Rahman Shiri - Finnish Inst Occupat Hlth, Helsinki, Finland
Tariq Jamal Siddiqi - Dow Univ Hlth Sci, Dept Med, Karachi, Pakistan
Joao Pedro Silva - Universidade do Porto
Jasvinder A. Singh - University of Alabama
Amin Soheili - Semnan University
Emma Elizabeth Spurlock - University of Washington
Cassandra E. I. Szoeke - University of Melbourne
Rafael Tabares-Seisdedos - Universitat de València
Biruk Wogayehu Taddele - ArbaminchCollege Hlth Sci, Dept Pharm, Arba Minch, Ethiopia
Bhaskar Thakur - Texas Tech Univ, Div Biostat & Epidemiol, El Paso, TX USA
Akhil Soman ThekkePurakkal - Publ Hlth Fdn India, Dis Burden Dept, Gurugram, India
Marcos Roberto Tovani-Palone - College Station Medical Center
Bach Xuan Tran - College Station Medical Center
Ravensara S. Travillian - University of Washington
Manjari Tripathi - College Station Medical Center
Gebiyaw Wudie Tsegaye - Bahir Dar University
Muhammad Shariq Usman - Dow Univ Hlth Sci, Dept Internal Med, Karachi, Pakistan
Marco Vacante - University of Catania
Diana Zuleika Velazquez - Autonomous University of Sinaloa
Narayanaswamy Venketasubramanian - Raffles Hosp, Raffles Neurosci Ctr, Singapore, Singapore
Simone Vidale - Infermi Hosp, Dept Neurol, Rimini, Italy
Vasily Vlassov - Supreme Council Of Health
Yuan-Pang Wang - Univ Sao Paulo, Dept Psychiat, Sao Paulo, Brazil
Jingkai Wei - George Washington University
Jordan Weiss - Univ Calif Berkeley, Dept Demog, Berkeley, CA USA
Abrha Hailay Weldemariam - Aksum University
Anders Wimo - Karolinska Institutet
Chenkai Wu - Duke Kunshan University
Ali Yadollahpour - University of Sheffield
Kazumasa Yamagishi - University of Tsukuba
Yordanos Gizachew Yeshitila - Arba Minch University
Naohiro Yonemoto - Natl Ctr Neurol & Psychiat, Dept Neuropsychopharmacol, Kodaira, Tokyo, Japan
Siddhesh Zadey - Duke University
Zhi-Jiang Zhang - Wuhan University
Christopher J. L. Murray - University of Washington
Theo Vos - University of Washington
GBD 2019 Collaborators
Publication Details: Alzheimer's & dementia : translational research & clinical interventions, Vol.7(1), pp.e12200-n/a
Publisher: Wiley
Number of pages: 28
Grant note: Gates Ventures, Seattle, WA Bill and Melinda Gates Foundation, Seattle, WA; Bill & Melinda Gates Foundation
Identifiers: 9914963508331
Academic Unit: Imam Abdulrahman Bin Faisal University; Taif University; King Saud University
Language: English
Resource Type: Journal article