Abstract
Psiadiararabin (
1) and its 6-desmethyl analogue, 5,3′-dihydroxy-7,2′,4′,5′-tetramethoxyflavone (
2), were converted by
C. elegans to their 3′-glucosides.
Microbial transformation of psiadiarabin and its 6-desmethoxy analogue 5,3′ dihydroxy-7,2′,4′,5′-tetramethoxyflavone by
Cunninghamella elegans NRRL 1392 gave the 3′-glucoside conjugates of the two flavones. Structural elucidation of these two new metabolites was achieved using 1D and 2D NMR spectroscopy and CIMS.