Glutathione is key to the synergistic enhancement of doxorubicin and etoposide by polyphenols in leukaemia cell lines

Journal article

Open access

Peer reviewed

A A Mahbub, C L Le Maitre, S L Haywood-Small, N A Cross and N Jordan-Mahy

Cell death & disease, Vol.6(12), pp.e2028-e2028

01/12/2015

PMCID: PMC4720910

PMID: 26720337

Abstract

Antineoplastic Combined Chemotherapy Protocols - pharmacology

Cell Line, Tumor

Doxorubicin - administration & dosage

Doxorubicin - pharmacology

Drug Synergism

Etoposide - administration & dosage

Etoposide - pharmacology

Glutathione - metabolism

Humans

Jurkat Cells

Leukemia, Lymphoid - drug therapy

Leukemia, Lymphoid - metabolism

Leukemia, Myeloid - drug therapy

Leukemia, Myeloid - metabolism

Polyphenols - administration & dosage

Polyphenols - pharmacology

Topoisomerase II Inhibitors - administration & dosage

Topoisomerase II Inhibitors - pharmacology

url

https://doi.org/10.1038/CDDIS.2015.379View

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Title: Glutathione is key to the synergistic enhancement of doxorubicin and etoposide by polyphenols in leukaemia cell lines
Creators - without role: A A Mahbub - Sheffield Hallam University
C L Le Maitre - Sheffield Hallam University
S L Haywood-Small - Sheffield Hallam University
N A Cross - Sheffield Hallam University
N Jordan-Mahy - Sheffield Hallam University
Publication Details: Cell death & disease, Vol.6(12), pp.e2028-e2028
Identifiers: 9931331408331
Academic Unit: Umm Al Qura University
Language: English
Resource Type: Journal article