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Green approach for the synthesis of 4-coumarin-4H-pyrans from 4-formylcoumarins and their antibacterial study
Journal article   Peer reviewed

Green approach for the synthesis of 4-coumarin-4H-pyrans from 4-formylcoumarins and their antibacterial study

Alpana Saxena, Lokesh Shastri and Vinay Sunagar
Synthetic communications, Vol.47(17), pp.1570-1576
01/01/2017

Abstract

4-Formylcoumarin eco-friendly malononitrile triethylamine
A series of 4H-pyranocoumarin derivatives have been successfully synthesized under eco-friendly condition using triethylamine as a catalyst in short reaction time with excellent yield at room temperature. All the synthesized compounds were characterized by spectral analysis and screened for their antibacterial activity against Escherichia coli and Staphylococcus aureus, the results are quite promising.

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