Abstract
Eco-friendly and inexpensive syntheses of metal-based nanocomposites is now gaining attention for their potential exploitation in biomedical and environmental fields. In this study, green method was applied to synthesize chitosan-modified platinum-doped silver nanocomposites (Ch-Pt-Ag NCs) using leaf extract of Desmostachya bipinnata, a plant with several medicinal values. Synthesis of Ch-Pt-Ag NCs was proven by XRD, SEM, FTIR, and TGA characterizations. Photocatalytic and biological activities of green-prepared Ch-Pt-Ag NCs were further explored. Crystallites of Ch-Pt-Ag NCs exhibited a mean size of 24 nm measured by XRD. SEM analysis indicated the formation of cubic and rod-shaped structures of Ch-Pt-Ag NCs. Functional groups present in plant extract were responsible for stabilizing and capping of Ch-Pt-Ag NCs, which were confirmed by FTIR analysis. Green synthesized Ch-Pt-Ag NCs exhibited dose -dependent anti-inflammatory and larvicidal (anti-dengue) activities. Green prepared Ch-Pt-Ag NCs exerted very low toxicity in Brine shrimp lethality assay indicated the biocompatible nature of synthe-sized nanostructures. The Ch-Pt-Ag NCs were also examined as a photocatalytic agent, resulting in 98% degradation of Rhodamine dye. Green synthesized Ch-Pt-Ag NCs with great biological and photocatalytic activities warrants further research on its biomedical and environmental fields. (c) 2022 The Author(s). Published by Elsevier B.V. on behalf of King Saud University. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).