Abstract
COVID-19 is a contagious disease with a high case fatality and morbidity rate associated with a pandemic outbreak. Transmission of SARS-CoV-2 infection can take place via airborne transmission, droplet, or direct contact. Implementing effective preventive measures remains the most important option available for dealing with SARS-CoV-2. The effectiveness of surface disinfectants, sanitizers, and personal protective equipment is totally based on three factors-strength, composition, and material-to determine whether or not preventive measures will be effective. Coronavirus transmission is disrupted by the use of an alcohol-based sanitizer containing 62% to 95% alcohol, which can denature viral proteins. However, hand sanitizers and disinfectants used on a regular daily basis may harm the skin's surface. In this study, we cover the importance of selecting the right disinfectant, the proper method of hand sanitization, and how to minimize the harmful effects on the skin while enhancing the inhibitory activity that could be a viable prescription for fighting COVID-19.