Abstract
A novel coronavirus (COVID-19) is a newly discovered virus in 2019 in Wuhan, China. Globally around the world, healthcare professionals (HCP), including nurses, are the front line health workers (FHW), considered as a vital member of the team trying to save several people's lives. Although leading health organizations and scientific papers consistently addressed the HCP challenging role concerning multidisciplinary approaches and support systems, along with evidence-based research implications for delivering the best possible quality care, this review resulted in four primary categories, such as challenges, domains, support systems (code of ethics), and evidence-based synthesis of health policy. A step further, this article will detail the tremendous role of brave healthcare workers, including nurses and pharmacists who proved themselves as health warriors, along with the key issues about the nurses' perspectives on the impact of COVID-19, and to debunk the mixed messages what is being reported every day is a virtual drive for nurses focusing on the significant domains of nursing practices as a motivating factor amid COVID-19.