Abstract
1,2-Bis(4-amino-5-mercapto-1,2,4-triazol-3-yl)benzene (
3
) was synthesized from the reaction of phthalic acid with thiocarbohydrazide. Reaction of
3
with ethylbromoactate or ethylchloroacetate afforded compound
4
. Heating of
3
with chloroacetyl chloride or chloroacetic acid gave triazolothiadiazinone
5
and
8
, respectively. Refluxing of
3
with phenacyl bromide resulted in benzoylmethylthiotriazole
9
. Treatment of
3
with chloroacetamide or benzyl chloride yielded
11
and
13
, respectively. Condensation of
3
with benzaldehyde or
m
-nitrobenzaldehyde gave the products
14a
and
14b
in the ratio 1:2, and
15
, respectively.