Abstract
Upper gastrointestinal tract endoscopy is frequently used to diagnose a many pathological conditions affect the upper gastrointestinal tract, and when combined with biopsy they provide the exact diagnosis for further management. A retrospective study was conducted in the KAASH Hospital, Taif, KSA. Histopathological assessment of upper GIT endoscopic biopsies from patients suffering from upper GIT disorder were done at the histopathology Lab, and the important clinical data were collected from medical records of all patients from January 2021 to April 2021. A total 85 case enrolled in the study, 54.1% were males and 45.9% were females; the male to female ratio was 1.7:1, their ages ranged from 11 to 103 years old with a mean age of 47.8 +/- SD. 21.2. The most common patient's complaints were dyspepsia 28.6% and heart burn 23.8%. The most frequent endoscopic findings in the study cases were gastritis 28%, followed by hiatus hernia 25%, reflux esophagitis and incompetent cardia 15%, duodenitis 10%, malignant gastric masses 7.5%, peptic ulcers 5% and finally esophageal mass 2.5%. While the normal endoscopic finding observed in 7.5%. The histopathological finding of examined endoscopic biopsies in the study group, acute and chronic nonspecific gastritis 37.6%. chronic gastritis with Helicobacter pylori infection 23.5%, esophagitis 10.5%, duodenitis 8.2%, Barret's esophagus 1.2%, gastric carcinoma 5.8% and esophageal cancer 1.2%. Endoscopic examination of patients with upper GIT disorders is incomplete without histopathological assessment of biopsies and so, the combinations of two procedures play an important role in diagnosis and management of upper gastrointestinal tract disorders that frequently increased in all ages and in both genders.