Abstract
Histopathological changes have been recorded in the gills, liver and intestinal tissue of Labeo rohita from River Ravi receiving industrial waste. Varying concentrations of Pb and Cu were recorded in the liver, gills and intestine of Labeo rohita. The pronounced histopathological changes like degeneration, necrosis and disorganization of lamellae and hyperplasia of epithelial cells was observed in the gills of the fish collected from a polluted site as compared to the fish from a control site. The liver sections of Labeo rohita exhibited aggregation, hypertrophy of hepatocytes, cytoplasmic degeneration, hemolysis between hepatocytes, focal necrosis and degeneration. In the intestinal tissue of Labeo rohita prominent histopathological changes, including edema, atrophy in the mucosal layer, hemorrhage between blood vessels, blood congestion and aggregations of inflammatory cells were observed. The polluted water has caused more histopathological alterations in Labeo rohita. Comparison of histopathology in each organ of Labeo rohita showed a same degree of tissue damage in the gills, while aggregation of hepatocytes in the liver, and atrophy of the mucosal layer in intestinal tissue of L. rohita were more evident.