Abstract
Spring viremia of carp (SVC) is an important disease affecting cyprinids, mainly common carp Cyprinus carpio. The disease is widespread in European carp culture, where it causes significant morbidity and mortality. This study describes some Histopathological, Immunohistological, and Ultra-microscopical characteristics of infection by this virus in experimentally infected target species; common carp. In this study the pathological changes in naturally and experimentally infected fish existed mainly in the hepatopancreas, kidney, spleen and gills. On the other hand, the changes were evoked to a lesser extent in the intestine and brain. The alterations were ranging between minor degenerative changes to severe necrotic picture. Immunostaining and immunoflourescence studies revealed the presence of antigen in SVCV infected tissue specimens. Transmission Electron Microscopy studies of liver, kidney and spleen samples revealed the presence of pullet-shaped electron-dense intra-cytoplasmic particles, with approximate length of 180-200 nm and approximate width of 90-100 nm. These particles resemble the characteristics of Rhabdovirus viral particles. [A. Y. Gaafar, Tomas Vesely, T. Nakai, E. M. El-Manakhly, M. K. Soliman, H. Soufy, Mona S. Zaki, Safinaz G. Mohamed, Amany M. Kenawy, M. S. El-Neweshy and A. Younes. Histopathological and Ultrastructural Study of Experimental Spring Viraemia of Carp (SVC) Infection of Common Carp with Comparison between Different Immunohistodignostic Techniques Efficacy. [Life Science Journal. 2011; 8(3):523-533] (ISSN: 1097-8135). http://www.lifesciencesite.com. #82