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Hydrazonoyl halides in heterocycles: synthesis and anti-microbial activity of new 1,2,4-benzotriazine and bis-1,2,4-benzotriazine derivatives
Journal article   Peer reviewed

Hydrazonoyl halides in heterocycles: synthesis and anti-microbial activity of new 1,2,4-benzotriazine and bis-1,2,4-benzotriazine derivatives

Asma M. Mahran, Thoraya A. Farghaly and Afaf A. Nada
Research on chemical intermediates, Vol.41(5), pp.2961-2969
01/05/2015
DOI: https://doi.org/10.1007/s11164-013-1404-9

Abstract

Chemistry Chemistry, Multidisciplinary Physical Sciences Science & Technology
Starting from o-dianisidine 1 or o-anisidine 7 with ethyl N-araylhydrazono chloroacetate 2a-d, a series of new 1,2,4-benzotriazine 4a-d, 9, and bis-1,2,4-benzotriazine 6a-d derivatives were prepared. The mechanisms of the studied reactions have been discussed and the anti-microbial activity of the isolated products has been evaluated.

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