Abstract
Background: Laparoscopic sleeve gastrectomy has become the treatment of choice by many surgeons, nowadays. The gallstones incidence in sleeve gastrectomy is reported in many studies with still no definite risk factor determined for its causes. Methods: A retrospective study was conducted in King Fahad University Hospital in Al-Khobar, Saudi Arabia. The included patients were [mention glimpse of inclusion criteria]. A detailed personal and history of diseases was obtained from each patient. Incidence and 95% confidence interval were calculated. Cox regression analysis was used to predict risk factors associated with high risk of gallstone formation. Results: The incidence of gallstone after sleeve gastrectomy was 3.81% which was the same as symptomatic gallstones. there was significant increase in BMI in patients who developed gallstone more than patients with no gallstones group [p-value = 0.02]. However, the rate of change of BMI did not increase the risk for gallstone formation. Furthermore, the risk factors associated with time to develop gallstones was being single, high BMI, preoperative lipase HR = 1.05, SE = 0.02, P-value = 0.018], cholesterol, LDL and postoperative total bilirubin, LDL and HDL. Conclusion: The risk factors associated with time to develop gallstones were marital status, BMI, preoperative lipase, cholesterol, LDL and postoperative total bilirubin, LDL and HDL.