Abstract
Eosinophilic gastroenteritis is a rare and heterogeneous disorder characterized by eosinophilic infiltration into one or more layers of gastrointestinal tract. Although it can involve any part of the gastrointestinal tract, the stomach and the proximal small bowel are the most common sites of involvement. Ileocolitis location seems to be quite rare. It should be suspected in patients having gastrointestinal discomfort along with peripheral eosinophilia and where other diseases associated with peripheral eosinophilia had ruled out. We report herein two cases of Tunisian patients who presented with an unusual location of the disease at the terminal ileum and colon.