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Immunofluorescent localization of beta2-microglobulin in the human kidney
Journal article   Peer reviewed

Immunofluorescent localization of beta2-microglobulin in the human kidney

B S Ooi, S C Rubin, A J Pesce and V E Pollak
Transplantation, Vol.24(1), pp.1-3
07/1977
DOI: https://doi.org/10.1097/00007890-197707000-00001
PMID: 70090

Abstract

Basement Membrane - immunology beta 2-Microglobulin - analysis Beta-Globulins - analysis Fluorescent Antibody Technique Humans Immune Sera Kidney - immunology Kidney Glomerulus - immunology
Using antisera to human beta2-microglobulin and an immunofluorescent technique, beta2-microglobulin was found to be localized along tubular and glomerular basement membranes of renal bipsies studied. Since beta2-microglobulin is a subunit of HLA preparations, it may also serve as an indirect marker for the presence of HLA antigens in these structures.

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