Immunogenicity and Safety of Beta-Adjuvanted Recombinant Booster Vaccine

Odile Launay; Marine Cachanado; Liem B. Luong Nguyen; Laetitia Ninove; Marie Lachâtre; Inès Ben Ghezala; Marc Bardou; Catherine Schmidt-Mutter; Karine Lacombe; Fabrice Laine; Jean-Sébastien Allain; Elisabeth Botelho-Nevers; Marie-Pierre Tavolacci; Christian Chidiac; Patricia Pavese; Bertrand Dussol; Stéphane Priet; Dominique Deplanque; Amel Touati; Laureen Curci; Eleine Konate; Nadine Ben Hamouda; Anissa Besbes; Eunice Nubret; Florence Capelle; Laurence Berard; Alexandra Rousseau; Eric Tartour; Tabassome Simon; Xavier de Lamballerie

doi:10.1056/NEJMc2206711

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Immunogenicity and Safety of Beta-Adjuvanted Recombinant Booster Vaccine

Journal article

Open access

Peer reviewed

Immunogenicity and Safety of Beta-Adjuvanted Recombinant Booster Vaccine

Odile Launay, Marine Cachanado, Liem B. Luong Nguyen, Laetitia Ninove, Marie Lachâtre, Inès Ben Ghezala, Marc Bardou, Catherine Schmidt-Mutter, Karine Lacombe, Fabrice Laine, …

The New England journal of medicine, Vol.387(4), pp.374-376

28/07/2022

DOI: https://doi.org/10.1056/NEJMc2206711

PMID: 35767474

Abstract

Coronavirus

Infectious Disease

Vaccines

Viral Infections

In a small trial of boost immunization with the mRNA vaccine originally received or with heterologous boosting with spike proteins from the original strain or the beta variant, the beta-adjuvanted booster resulted in the highest titers of antibody and activated T cells 2 weeks later.

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Title: Immunogenicity and Safety of Beta-Adjuvanted Recombinant Booster Vaccine
Creators - without role: Odile Launay - Sorbonne Paris Cité
Marine Cachanado - Hôpital Saint-Antoine
Liem B. Luong Nguyen - Hôpital Cochin
Laetitia Ninove - Aix-Marseille University
Marie Lachâtre - Hôpital Cochin
Inès Ben Ghezala - University Hospital, Dijon, France
Marc Bardou - University Hospital, Dijon, France
Catherine Schmidt-Mutter - Hôpitaux Universitaires de Strasbourg
Karine Lacombe - Université Sorbonne Nouvelle
Fabrice Laine - Centre Hospitalier Universitaire (CHU) Rennes, Rennes, France
Jean-Sébastien Allain - Centre Hospitalier Universitaire (CHU) Rennes, Rennes, France
Elisabeth Botelho-Nevers - Centre Hospitalier Universitaire de Saint-Étienne
Marie-Pierre Tavolacci - Centre Hospitalier Universitaire de Rouen
Christian Chidiac - Hospices Civils de Lyon
Patricia Pavese - Centre Hospitalier Universitaire de Grenoble
Bertrand Dussol - Marseille Public University Hospital System
Stéphane Priet - Aix-Marseille University
Dominique Deplanque - Centre Hospitalier Universitaire de Lille
Amel Touati - Hôpital Saint-Antoine
Laureen Curci - Hôpital Cochin
Eleine Konate - Hôpital Cochin
Nadine Ben Hamouda - Hôpital Européen Georges-Pompidou
Anissa Besbes - Hôpital Européen Georges-Pompidou
Eunice Nubret - Assistance Publique – Hôpitaux de Paris
Florence Capelle - Assistance Publique – Hôpitaux de Paris
Laurence Berard - Hôpital St. Antoine, Paris, France
Alexandra Rousseau - Hôpital St. Antoine, Paris, France
Eric Tartour - Hôpital Européen Georges-Pompidou
Tabassome Simon - Sorbonne Université, Paris, France
Xavier de Lamballerie - Aix-Marseille University
Publication Details: The New England journal of medicine, Vol.387(4), pp.374-376
Publisher: Massachusetts Medical Society
Identifiers: 9919302108331
Academic Unit: Northern Borders University
Language: English
Resource Type: Journal article