Abstract
The purpose of this study was to evaluate the impact of R-heart failure (R-hf) risk score on all-cause mortality in acute heart failure (AHF) patients in the Middle East.
Data was analyzed from 776 consecutive patients. R-hf risk score were derived by multiplying (eGFR (mL/min), left ventricular ejection fraction (%) and hemoglobin levels (g/dL)) and then by dividing by NT proBNP (pg/ml). R-hf scores of <5 indicated high risk, 5-<10 indicated moderate risk, 10-<50 indicated low risk while R-hf scores of ≥50 indicated minimal risk. Analyses were made using univariate and multivariate logistic regression techniques.
The overall mean age of the cohort was 62±14 years, 63% (n=484) were males. The proportion of patients that had high, moderate, low, and minimal risk was 42% (n=324), 16% (n=127), 31% (n=242), and 11% (n=83), respectively. Adjusting for demographic and clinical characteristics as well as medications use in the multivariate logistic regression models, AHF patients with high risk (R-hf score, <5) were associated with higher 12-month all-cause mortality when compared to those with low (adjusted odds ratio (aOR), 3.10; 95% confidence interval (CI): 1.56-6.20; p=0.001) and minimal (aOR, 3.84; 95% CI: 1.23-12.0; p=0.021) risk.
Lower R-hf risk scores (www.hfriskcalc.in) were associated with higher risk of all-cause 12-month mortality in AHF patients in the Middle East.