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Improved method of labeling thyroid hormones with radioiodine
Journal article

Improved method of labeling thyroid hormones with radioiodine

E. Hallaba, G. El-Shaboury and Atomic Energy Establishment, Cairo
J. Nucl. Med., v. 15, no. 4, pp. 270-272
01/04/1974

Abstract

CHEMICAL REACTION YIELD ETHANOL IODINE 131- RADIOCHEMISTRY LABELLED COMPOUNDS N40420 -Chemistry-Radiochemistry & Nuclear Chemistry- Properties of Radioactive Materials THYROXINE- LABELLING
The parameters of the isotopic exchange reaction between nonradioactive thyroxine or tniiodothyronine dissolved in ethyl alcohol with radioiodine extracted in ether were investigated. The effect of the concentration of carrier iodine on the yield of labeling as well as the different factors leading to its formation are discussed. A radiochemical yield of 95% /sup 131/I-thyroxine is obtained within 10-15.min. The method is very simple and favorable for very short-lived radioiodines. (auth)

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