Abstract
The influence of using saline solution as mixing and curing liquid on some characteristics of beta-dicalcium silicate (beta-C2S) and biphasic compound tri-calcium phosphate/hydroxyapatite (TCP/HAp) bio-ceramics was investigated. beta-C2S (27-30 nm) was prepared by solid state reaction at 1450 degrees C, while biphasic compound TCP/HAp (7-15 nm) was synthesized from an aqueous solution of Ca(NO3)(2)center dot 4H(2)O and (NH4)(2)HPO4 center dot 12H(2)O by chemical precipitation method. Setting times, compressive strength, pH values, X-ray diffraction analysis, infrared spectroscopy, scanning electron microscopy (SEM) were investigated. The evaluation of cytotoxicity of both calcium silicate and biphasic compounds to human gingival fibroblasts was carried out. The use of saline solution as mixing and immersing liquid shortened the setting time for the two bio-cements. TCP/HAp did not show any mechanical strength but beta-C2S showed good strength values. Both synthesized compounds showed a moderate cytotoxicity and both materials were effective in a no significant way. (C) 2015 Elsevier B.V. All rights reserved.