Insights from a Pan India Sero-Epidemiological survey (Phenome-India Cohort) for SARS-CoV2

Salwa Naushin; Viren Sardana; Rajat Ujjainiya; Nitin Bhatheja; Rintu Kutum; Akash Kumar Bhaskar; Shalini Pradhan; Satyartha Prakash; Raju Khan; Birendra Singh Rawat; Karthik Bharadwaj Tallapaka; Mahesh Anumalla; Giriraj Ratan Chandak; Amit Lahiri; Susanta Kar; Shrikant Ramesh Mulay; Madhav Nilakanth Mugale; Mrigank Srivastava; Shaziya Khan; Anjali Srivastava; Bhawana Tomar; Murugan Veerapandian; Ganesh Venkatachalam; Selvamani Raja Vijayakumar; Ajay Agarwal; Dinesh Gupta; Prakash M. Halami; Muthukumar Serva Peddha; Gopinath M. Sundaram; Ravindra P. Veeranna; Anirban Pal; Vinay Kumar Agarwal; Anil Ku Maurya; Ranvijay Kumar Singh; Ashok Kumar Raman; Suresh Kumar Anandasadagopan; Parimala Karuppanan; Subramanian Venkatesan; Harish Kumar Sardana; Anamika Kothari; Rishabh Jain; Anupama Thakur; Devendra Singh Parihar; Anas Saifi; Jasleen Kaur; Virendra Kumar; Avinash Mishra; Iranna Gogeri; Geethavani Rayasam; Praveen Singh; Rahul Chakraborty; Gaura Chaturvedi; Pinreddy Karunakar; Rohit Yadav; Sunanda Singhmar; Dayanidhi Singh; Sharmistha Sarkar; Purbasha Bhattacharya; Sundaram Acharya; Vandana Singh; Shweta Verma; Drishti Soni; Surabhi Seth; Sakshi Vashisht; Sarita Thakran; Firdaus Fatima; Akash Pratap Singh; Akanksha Sharma; Babita Sharma; Manikandan Subramanian; Yogendra S. Padwad; Vipin Hallan; Vikram Patial; Damanpreet Singh; Narendra Vijay Tripude; Partha Chakrabarti; Sujay Krishna Maity; Dipyaman Ganguly; Jit Sarkar; Sistla Ramakrishna; Balthu Narender Kumar; Kiran A. Kumar; Sumit G. Gandhi; Piyush Singh Jamwal; Rekha Chouhan; Vijay Lakshmi Jamwal; Nitika Kapoor; Debashish Ghosh; Ghanshyam Thakkar; Umakanta Subudhi; Pradip Sen; Saumya Ray Chaudhury; Rashmi Kumar; Pawan Gupta; Amit Tuli; Deepak Sharma; Rajesh P. Ringe; D. Amarnarayan; Mahesh Kulkarni; Dhansekaran Shanmugam; Mahesh S. Dharne; Sayed G. Dastager; Rakesh Joshi; Amita P. Patil; Sachin N. Mahajan; Abujunaid Habib Khan; Vasudev Wagh; Rakesh Kumar Yadav; Ajinkya Khilari; Mayuri Bhadange; Arvindkumar H. Chaurasiya; Shabda E. Kulsange; Krishna Khairnar; Shilpa Paranjape; Jatin Kalita; Narahari G. Sastry; Tridip Phukan; Prasenjit Manna; Wahengbam Romi; Pankaj Bharali; Dibyajyoti Ozah; Ravi Kumar Sahu; Elapavalooru Vssk Babu; Rajeev Sukumaran; Aiswarya R. Nair; Prajeesh Kooloth Valappil; Anoop Puthiyamadam; Adarsh Velayudhanpillai; Kalpana Chodankar; Samir Damare; Yennapu Madhavi; Ved Varun Aggarwal; Sumit Dahiya; Anurag Agrawal; Debasis Dash; Shantanu Sengupta

doi:10.7554/eLife.66537

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Insights from a Pan India Sero-Epidemiological survey (Phenome-India Cohort) for SARS-CoV2

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Peer reviewed

Insights from a Pan India Sero-Epidemiological survey (Phenome-India Cohort) for SARS-CoV2

Salwa Naushin, Viren Sardana, Rajat Ujjainiya, Nitin Bhatheja, Rintu Kutum, Akash Kumar Bhaskar, Shalini Pradhan, Satyartha Prakash, Raju Khan, Birendra Singh Rawat, …

eLife, Vol.10

20/04/2021

DOI: https://doi.org/10.7554/eLife.66537

PMID: 33876727

Abstract

Biology

Life Sciences & Biomedicine

Life Sciences & Biomedicine - Other Topics

Science & Technology

To understand the spread of SARS-CoV2, in August and September 2020, the Council of Scientific and Industrial Research (India) conducted a serosurvey across its constituent laboratories and centers across India. Of 10,427 volunteers, 1058 (10.14%) tested positive for SARS-CoV2 anti-nucleocapsid (anti-NC) antibodies, 95% of which had surrogate neutralization activity. Three-fourth of these recalled no symptoms. Repeat serology tests at 3 (n = 607) and 6 (n = 175) months showed stable anti-NC antibodies but declining neutralization activity. Local seropositivity was higher in densely populated cities and was inversely correlated with a 30-day change in regional test positivity rates (TPRs). Regional seropositivity above 10% was associated with declining TPR. Personal factors associated with higher odds of seropositivity were high-exposure work (odds ratio, 95% confidence interval, p value: 2.23, 1.92-2.59, <0.0001), use of public transport (1.79, 1.43-2.24, <0.0001), not smoking (1.52, 1.16-1.99, 0.0257), non-vegetarian diet (1.67, 1.41-1.99, <0.0001), and B blood group (1.36, 1.15-1.61, 0.001).

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Title: Insights from a Pan India Sero-Epidemiological survey (Phenome-India Cohort) for SARS-CoV2
Creators - without role: Salwa Naushin - Institute of Genomics and Integrative Biology
Viren Sardana - Institute of Genomics and Integrative Biology
Rajat Ujjainiya - Institute of Genomics and Integrative Biology
Nitin Bhatheja - Institute of Genomics and Integrative Biology
Rintu Kutum - Institute of Genomics and Integrative Biology
Akash Kumar Bhaskar - Institute of Genomics and Integrative Biology
Shalini Pradhan - Institute of Genomics and Integrative Biology
Satyartha Prakash - Institute of Genomics and Integrative Biology
Raju Khan - Academy of Scientific and Innovative Research
Birendra Singh Rawat - Academy of Scientific and Innovative Research
Karthik Bharadwaj Tallapaka - Centre for Cellular and Molecular Biology
Mahesh Anumalla - Centre for Cellular and Molecular Biology
Giriraj Ratan Chandak - Academy of Scientific and Innovative Research
Amit Lahiri - Academy of Scientific and Innovative Research
Susanta Kar - Academy of Scientific and Innovative Research
Shrikant Ramesh Mulay - Academy of Scientific and Innovative Research
Madhav Nilakanth Mugale - Academy of Scientific and Innovative Research
Mrigank Srivastava - Academy of Scientific and Innovative Research
Shaziya Khan - Academy of Scientific and Innovative Research
Anjali Srivastava - Academy of Scientific and Innovative Research
Bhawana Tomar - Academy of Scientific and Innovative Research
Murugan Veerapandian - Academy of Scientific and Innovative Research
Ganesh Venkatachalam - Academy of Scientific and Innovative Research
Selvamani Raja Vijayakumar - Central Electrochemical Research Institute
Ajay Agarwal - Academy of Scientific and Innovative Research
Dinesh Gupta - Central Electronics Engineering Research Institute
Prakash M. Halami - Academy of Scientific and Innovative Research
Muthukumar Serva Peddha - Academy of Scientific and Innovative Research
Gopinath M. Sundaram - Academy of Scientific and Innovative Research
Ravindra P. Veeranna - Academy of Scientific and Innovative Research
Anirban Pal - Academy of Scientific and Innovative Research
Vinay Kumar Agarwal - Central Institute of Medicinal and Aromatic Plants
Anil Ku Maurya - College Station Medical Center
Ranvijay Kumar Singh - Academy of Scientific and Innovative Research
Ashok Kumar Raman - Central Institute of Mining and Fuel Research
Suresh Kumar Anandasadagopan - Academy of Scientific and Innovative Research
Parimala Karuppanan - Central Leather Research Institute
Subramanian Venkatesan - Academy of Scientific and Innovative Research
Harish Kumar Sardana - Central Scientific Instruments Organisation
Anamika Kothari - Central Scientific Instruments Organisation
Rishabh Jain - Academy of Scientific and Innovative Research
Anupama Thakur - Academy of Scientific and Innovative Research
Devendra Singh Parihar - Academy of Scientific and Innovative Research
Anas Saifi - Academy of Scientific and Innovative Research
Jasleen Kaur - Academy of Scientific and Innovative Research
Virendra Kumar - Central Scientific Instruments Organisation
Avinash Mishra - Academy of Scientific and Innovative Research
Iranna Gogeri - Academy of Scientific and Innovative Research
Geethavani Rayasam - Academy of Scientific and Innovative Research
Praveen Singh - Institute of Genomics and Integrative Biology
Rahul Chakraborty - Institute of Genomics and Integrative Biology
Gaura Chaturvedi - Institute of Genomics and Integrative Biology
Pinreddy Karunakar - Institute of Genomics and Integrative Biology
Rohit Yadav - CSIR, Inst Genom & Integrat Biol, New Delhi, India
Sunanda Singhmar - CSIR, Inst Genom & Integrat Biol, New Delhi, India
Dayanidhi Singh - Institute of Genomics and Integrative Biology
Sharmistha Sarkar - Institute of Genomics and Integrative Biology
Purbasha Bhattacharya - Institute of Genomics and Integrative Biology
Sundaram Acharya - Institute of Genomics and Integrative Biology
Vandana Singh - Institute of Genomics and Integrative Biology
Shweta Verma - Institute of Genomics and Integrative Biology
Drishti Soni - Institute of Genomics and Integrative Biology
Surabhi Seth - Institute of Genomics and Integrative Biology
Sakshi Vashisht - Institute of Genomics and Integrative Biology
Sarita Thakran - Institute of Genomics and Integrative Biology
Firdaus Fatima - Institute of Genomics and Integrative Biology
Akash Pratap Singh - CSIR, Inst Genom & Integrat Biol, New Delhi, India
Akanksha Sharma - Institute of Genomics and Integrative Biology
Babita Sharma - Institute of Genomics and Integrative Biology
Manikandan Subramanian - Institute of Genomics and Integrative Biology
Yogendra S. Padwad - Academy of Scientific and Innovative Research
Vipin Hallan - Academy of Scientific and Innovative Research
Vikram Patial - Academy of Scientific and Innovative Research
Damanpreet Singh - Academy of Scientific and Innovative Research
Narendra Vijay Tripude - Academy of Scientific and Innovative Research
Partha Chakrabarti - Academy of Scientific and Innovative Research
Sujay Krishna Maity - Indian Institute of Chemical Biology
Dipyaman Ganguly - Academy of Scientific and Innovative Research
Jit Sarkar - Academy of Scientific and Innovative Research
Sistla Ramakrishna - Academy of Scientific and Innovative Research
Balthu Narender Kumar - Indian Institute of Chemical Technology
Kiran A. Kumar - Indian Institute of Chemical Technology
Sumit G. Gandhi - Academy of Scientific and Innovative Research
Piyush Singh Jamwal - Indian Institute of Integrative Medicine
Rekha Chouhan - Indian Institute of Integrative Medicine
Vijay Lakshmi Jamwal - Academy of Scientific and Innovative Research
Nitika Kapoor - Academy of Scientific and Innovative Research
Debashish Ghosh - Academy of Scientific and Innovative Research
Ghanshyam Thakkar - Indian Institute of Petroleum
Umakanta Subudhi - Academy of Scientific and Innovative Research
Pradip Sen - Academy of Scientific and Innovative Research
Saumya Ray Chaudhury - Academy of Scientific and Innovative Research
Rashmi Kumar - Academy of Scientific and Innovative Research
Pawan Gupta - Academy of Scientific and Innovative Research
Amit Tuli - Academy of Scientific and Innovative Research
Deepak Sharma - Academy of Scientific and Innovative Research
Rajesh P. Ringe - Institute of Microbial Technology
D. Amarnarayan - CSIR, Natl Aerosp Labs, Bengaluru, India
Mahesh Kulkarni - Academy of Scientific and Innovative Research
Dhansekaran Shanmugam - Academy of Scientific and Innovative Research
Mahesh S. Dharne - Academy of Scientific and Innovative Research
Sayed G. Dastager - Academy of Scientific and Innovative Research
Rakesh Joshi - Academy of Scientific and Innovative Research
Amita P. Patil - CSIR, Natl Chem Lab, Pune, Maharashtra, India
Sachin N. Mahajan - CSIR, Natl Chem Lab, Pune, Maharashtra, India
Abujunaid Habib Khan - Academy of Scientific and Innovative Research
Vasudev Wagh - Academy of Scientific and Innovative Research
Rakesh Kumar Yadav - Academy of Scientific and Innovative Research
Ajinkya Khilari - Academy of Scientific and Innovative Research
Mayuri Bhadange - Academy of Scientific and Innovative Research
Arvindkumar H. Chaurasiya - Academy of Scientific and Innovative Research
Shabda E. Kulsange - Academy of Scientific and Innovative Research
Krishna Khairnar - Academy of Scientific and Innovative Research
Shilpa Paranjape - CSIR, Natl Environm Engn Res Inst, Nagpur, Maharashtra, India
Jatin Kalita - CSIR, North East Inst Sci & Technol, Jorhat, Assam, India
Narahari G. Sastry - CSIR, North East Inst Sci & Technol, Jorhat, Assam, India
Tridip Phukan - CSIR, North East Inst Sci & Technol, Jorhat, Assam, India
Prasenjit Manna - CSIR, North East Inst Sci & Technol, Jorhat, Assam, India
Wahengbam Romi - CSIR, North East Inst Sci & Technol, Jorhat, Assam, India
Pankaj Bharali - CSIR, North East Inst Sci & Technol, Jorhat, Assam, India
Dibyajyoti Ozah - CSIR, North East Inst Sci & Technol, Jorhat, Assam, India
Ravi Kumar Sahu - Academy of Scientific and Innovative Research
Elapavalooru Vssk Babu - Academy of Scientific and Innovative Research
Rajeev Sukumaran - Academy of Scientific and Innovative Research
Aiswarya R. Nair - CSIR, Natl Inst Interdisciplinary Sci & Technol, Thiruvananthapuram, Kerala, India
Prajeesh Kooloth Valappil - Academy of Scientific and Innovative Research
Anoop Puthiyamadam - Academy of Scientific and Innovative Research
Adarsh Velayudhanpillai - CSIR, Natl Inst Interdisciplinary Sci & Technol, Thiruvananthapuram, Kerala, India
Kalpana Chodankar - Academy of Scientific and Innovative Research
Samir Damare - Academy of Scientific and Innovative Research
Yennapu Madhavi - Academy of Scientific and Innovative Research
Ved Varun Aggarwal - Academy of Scientific and Innovative Research
Sumit Dahiya - Academy of Scientific and Innovative Research
Anurag Agrawal - CSIR, Inst Genom & Integrat Biol, New Delhi, India
Debasis Dash - CSIR, Inst Genom & Integrat Biol, New Delhi, India
Shantanu Sengupta - CSIR, Inst Genom & Integrat Biol, New Delhi, India
Publication Details: eLife, Vol.10
Publisher: eLIFE SCIENCES PUBL LTD
Number of pages: 13
Grant note: MLP-2007; GAP-0192 / CSIR; Council of Scientific & Industrial Research (CSIR) - India GAP-0192 / Department of Science and Technology, India; Department of Science & Technology (India)
Identifiers: 9922299008331
Academic Unit: King Khalid University
Language: English
Resource Type: Journal article