Abstract
Objective: To compare the effect of temporary fixed restorations to final fixed restora-tions on gingival health of abutment tooth by evaluating the level of IL-1 beta in gingival crevicular fluid (GCF) as an inflammatory biomarker.
Subjects and methods: It was a nonrandomized prospective observational study. Samples of GCF were collected from 24 participants with provisional and permanent definitive full-coverage restorations with subgingival margin placements at three intervals for each participant: Interval 1, after preparation and immediately before cementation of temporary fixed restoration. Interval 2, after two weeks of temporization and before receiving the final fixed restoration. Interval 3, after two weeks of final fixed restorations. GCF were collected from gingival crevice of the abutment tooth by pre-prepared filter paper with dimensions of 2mmx13mm. They were prepared for IL-1 beta concentration assay by enzyme-linked immuno sorbent assay- analysis (ELIZA).
Results: Were analyzed by SAS (R) software, Descriptive means and medians were used and the repeated ANVOA test was applied (1st interval) showed the highest level of IL-b (13.587 +/- 5.735). In 2nd interval the level of IL-beta was significantly reduced (9.602 +/- 3.279). While, in 3rd interval the level of IL-beta was the lowest (6.293 +/- 3.279).
Conclusion: The material and technique of fabrication of both temporary and final fixed restora-tions are critical for gingival health. PMMA CAD-CAM based temporary restorations showed to be compatible to gingival health by decreasing the level of IL-beta level, but the zirconia as a final fixed restoration showed to have optimum compatible effect on gingival health. (C) 2021 The Authors. Production and hosting by Elsevier B.V. on behalf of King Saud University.