Abstract
This study aims to evaluate the negative effects of consumption of two types of Energy drinks; Red Bull (RB) and Code Red (CR) at two levels of doses on liver functions and lipid metabolism in rats.Fourty male adult albino rats (weighing 80-100 g) were randomly assigned to five groups (8 rats per group) each was orally administered. Group 1 (control group), Group 2 and 3 received low doses of RBand CR (each 5ml/day per kg b.w), respectively, Group 4 and 5 received high doses of RB and CR (each 10 ml/day per kg b.w), respectively. At the end of the 31st day of experiment, liver functions and lipid profile were investigatedData revealed that energy drinks affected the liver enzymes activities (ALT, AST, and ALP). Also changed in serum total proteins and albumin which were highly significantly (P <= 0.05) affected at high doses of both energy. The results of total lipids, total cholesterol, triacylglycerols and LDL-cholesterol showed a significant lower levels of co administered lower or higher doses of RB or CR(5ml/day or 10 ml/day respectively), while the activity of serum FAS and ACC were significantly (P <= 0.05) higher in rats administered high doses of both energy drinks. Also, the values of serum glucose and insulin were significantly (P <= 0.05) higher in rats administered high doses of both energy drinks. These data emphasize that high doses of energy drinks were clearly effective of liver enzymes, glucose and fat metabolism.