Abstract
Gold and Selenium ions have been incorporated into hydroxyapatite (HAP) using the co-precipitation technique at different contributions of Au(III). The obtained compositions were inspected via X-ray diffraction (XRD), Fourier transforms infrared (FTIR), and field emission scanning electron microscopy (FESEM), transmission electron microscopy (TEM). Structural parameters showed that Au content has a noticeable role in altering HAP lattice. TEM images display that the grain width decreased from 30 nm in 0.0Au/Se-HAP to 15 nm in 0.8Au/Se-HAP. The c/a ratio denoted a slight distortion in lattice after Au(III) contribution. Moreover, the roughness average increased from 26.3 nm reaching 32.4 nm for the lowest and the highest additional Au(III) contents. The compositions of 0.4Au/Se-HAP and 0.6Au/Se-HAP showed low crystallinity with surface defects, subsequently the highest percentage in cell viability. Furthermore, the indirect bandgaps become narrow with increasing additional Au(III) contribution starting from 6.45 to 6.40 eV. The refractive index shows a decreasing trend from 1.61 to 1.59 with increasing the Au(III) content. Cell viability starts from 94.0 +/- 5% in 0.0Au/Se-HAP composition and increases gradually to more than 98.2 +/- 4% for 0.6Au/Se-HAP. This work might boost more exploration of Au/Se-HAP as a promising material for biomedical utilizations.