Abstract
The effect of tetrahydroaminoacridine (THA) on turnover kinetics of camel retina acetylcholinesterase has been investigated. The turnover number (Kcat) and specificity constant (Ksp) were 62.1 min‐1 and 9.92 × 105 (M. min)‐1 in the control system while the values for both parameters were lowered by 25‐68% and 48‐87% in the THA (0.05‐0.4 µM) treated systems respectively. Therefore, THA's effect on turnover number must be considered at the time of therapy to the Alzheimer's disease patients.