Abstract
Stomach cancer is the second leading cause of cancer-related mortality worldwide. The present study aimed to answer whether Helicobacter pylori associated is suspicious of gastric cancer as a cause for gastric biopsy over-diagnosis. In this descriptive retrospective study, we retrieved data referring to gastric biopsies for one year back from the Department of Pathology at King Salman Hospital, Hai'l, Northern Saudi Arabia. The study included data referring to gastric biopsies patients diagnosed during the period from October 2019 to November 2020. The most identified histopathological finding was chronic inflammation 179/192(93.2%) included 84/88(95.5%) males and 95/104(91.3%) females. Acute inflammation was identified in 6/192(3%) patients, included 2/88(2.3%) males and 4/104(3.8%) females. Benign lesions were diagnosed in 3/192(1.6%) cases, 1/88(1.13%) male and 2/104(1.92%) females. Carcinoma of the stomach was diagnosed in 3/192(1.6%) patients, included 1/88(1.13%) male and 2/104(1.92%). Females. There is an overuse of gastric endoscopic diagnosis. H. pylori infection is prevalent in Northern Saudi Arabia. It frequently makes confusion for gastric carcinoma. The incidence of gastric cancer and other benign stomach tumors is very low in Northern Saudi Arabia. Strict guidelines for gastric endoscopy is deemed necessary in Northern Saudi Arabia.