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Isolation and structure determination of the biologically active sphingolipids from marine sponge Haliclona species
Journal article   Peer reviewed

Isolation and structure determination of the biologically active sphingolipids from marine sponge Haliclona species

Seif-Eldin N. Ayyad, Saleh Omar S. Bahaffi and Nadia E. Hashish
Natural product research, Vol.23(1), pp.44-50
10/01/2009
DOI: https://doi.org/10.1080/14786410701768246
PMID: 18989826

Abstract

Chemistry Chemistry, Applied Chemistry, Medicinal Life Sciences & Biomedicine Pharmacology & Pharmacy Physical Sciences Science & Technology
In a continuation to our study on the marine sponge Haliclona species we have isolated three new cytotoxic components of sphingolipids (1-3). Methanolysis of the sphingolipid 1a-d in methanol produces fatty acid methyl ester. GC/MS was used to determine the length. The structure of each isolated compound has been determined on the basis of spectroscopic data and chemical evidence.

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