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Isolation, structural identification and biological characterization of two conopeptides from the Conus pennaceus venom
Journal article   Peer reviewed

Isolation, structural identification and biological characterization of two conopeptides from the Conus pennaceus venom

Mohammed Abdel-Wahab, Masahiro Miyashita, Yoshiyuki Ota, Hironori Juichi, Ryota Okabe, Moustafa Sarhan, Maged Fouda, Mohamed Abdel-Rahman, Samy Saber and Yoshiaki Nakagawa
Bioscience, biotechnology, and biochemistry, Vol.81(11), pp.2086-2089
02/11/2017
DOI: https://doi.org/10.1080/09168451.2017.1364966
PMID: 28831846

Abstract

Biochemistry & Molecular Biology Biotechnology & Applied Microbiology Chemistry Chemistry, Applied Food Science & Technology Life Sciences & Biomedicine Physical Sciences Science & Technology
A novel anti-mollusk conopeptide pn4c was isolated from the Conus pennaceus venom by repeated HPLC fractionation based on the activity against freshwater snails. The primary structure of pn4c was determined by the mass spectrometric de novo sequencing analysis. In addition, pn3a was isolated from the same fraction containing pn4c, as a peptide with unknown functions.

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