Abstract
Background and Objective: Grading the severity level is an extremely important procedure for correct diagnoses and personalized treatment schemes for acne. However, the acne grading criteria are not unified in the medical field. This work aims to develop an acne diagnosis system that can be generalized to various criteria. Methods: A unified acne grading framework that can be generalized to apply referring to different grading criteria is developed. It imitates the global estimation of the dermatologist diagnosis in two steps. First, an adaptive image preprocessing method effectively filters meaningless information and enhances key information. Next, an innovative network structure fuses global deep features with local features to simulate the dermatologists’ comparison of local skin and global observation. In addition, a transfer fine-tuning strategy is proposed to transfer prior knowledge on one criterion to another criterion, which effectively improves the framework performance in case of insufficient data. Results: The Preprocessing method effectively filters meaningless areas and improves the performance of downstream models.The framework reaches accuracies of 84.52% and 59.35% on two datasets separately. Conclusions: The application of the framework on acne grading exceeds the state-of-the-art method by 1.71%, reaches the diagnostic level of a professional dermatologist and the transfer fine-tuning strategy improves the accuracy of 6.5% on the small data.